In-vitro activity of oxazolidinones against mycobacterium avium complex

Julius Peters, Kimi L. Kondo, Richard K. Lee, Carol K. Lin, Clark B. Inderlied

Research output: Contribution to journalArticlepeer-review

19 Scopus citations

Abstract

Options for treating disseminated Mycobacterium avium complex (MAC) disease have improved. However, efficacy is not always certain, resistance is common and rapidly bactericidal agents would improve efficacy and prevent resistance. Certain oxazolidinones were rested against MAC strains and inhibited growth at expected serum concentrations or lower. Activity correlated with hydrophobicity and one agent was bactericidal at concentrations two to five times greater than the MIC.

Original languageEnglish (US)
Pages (from-to)675-679
Number of pages5
JournalJournal of Antimicrobial Chemotherapy
Volume35
Issue number5
DOIs
StatePublished - May 1 1995
Externally publishedYes

ASJC Scopus subject areas

  • Pharmacology
  • Microbiology (medical)
  • Infectious Diseases
  • Pharmacology (medical)

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