The use of in situ curing biomimetic materials for cell ingrowth matrices in regenerative medicine, is described. Such materials must permit cell adhesion and cell infiltration from soft tissues. The biomimetic materials prove to be beneficial if they are consistent with the practice of minimally invasive surgery and are thus injectable as liquids and convert into solids in situ, in direct contact with tissues in the surgical site. It is observed that the Michael-type additions act as pathways towards in situ curing. The constraints placed upon chemical reactions to enable in situ crosslinking or polymerization are also substantial.