In situ curing biomimetic materials in regenerative medicine

J. A. Hubbell, M. P. Lutolf, G. Raeber, N. Tirelli, P. Van De Weterine, R. Schoenmakers

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

The use of in situ curing biomimetic materials for cell ingrowth matrices in regenerative medicine, is described. Such materials must permit cell adhesion and cell infiltration from soft tissues. The biomimetic materials prove to be beneficial if they are consistent with the practice of minimally invasive surgery and are thus injectable as liquids and convert into solids in situ, in direct contact with tissues in the surgical site. It is observed that the Michael-type additions act as pathways towards in situ curing. The constraints placed upon chemical reactions to enable in situ crosslinking or polymerization are also substantial.

Original languageEnglish
Title of host publicationTransactions - 7th World Biomaterials Congress
StatePublished - Dec 1 2004
Externally publishedYes
EventTransactions - 7th World Biomaterials Congress - Sydney, Australia
Duration: May 17 2004May 21 2004

Other

OtherTransactions - 7th World Biomaterials Congress
CountryAustralia
CitySydney
Period5/17/045/21/04

Fingerprint

Biomimetic materials
Curing
Tissue
Cell adhesion
Infiltration
Crosslinking
Surgery
Chemical reactions
Polymerization
Liquids
Regenerative Medicine

ASJC Scopus subject areas

  • Engineering(all)

Cite this

Hubbell, J. A., Lutolf, M. P., Raeber, G., Tirelli, N., Van De Weterine, P., & Schoenmakers, R. (2004). In situ curing biomimetic materials in regenerative medicine. In Transactions - 7th World Biomaterials Congress

In situ curing biomimetic materials in regenerative medicine. / Hubbell, J. A.; Lutolf, M. P.; Raeber, G.; Tirelli, N.; Van De Weterine, P.; Schoenmakers, R.

Transactions - 7th World Biomaterials Congress. 2004.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Hubbell, JA, Lutolf, MP, Raeber, G, Tirelli, N, Van De Weterine, P & Schoenmakers, R 2004, In situ curing biomimetic materials in regenerative medicine. in Transactions - 7th World Biomaterials Congress. Transactions - 7th World Biomaterials Congress, Sydney, Australia, 5/17/04.
Hubbell JA, Lutolf MP, Raeber G, Tirelli N, Van De Weterine P, Schoenmakers R. In situ curing biomimetic materials in regenerative medicine. In Transactions - 7th World Biomaterials Congress. 2004
Hubbell, J. A. ; Lutolf, M. P. ; Raeber, G. ; Tirelli, N. ; Van De Weterine, P. ; Schoenmakers, R. / In situ curing biomimetic materials in regenerative medicine. Transactions - 7th World Biomaterials Congress. 2004.
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