Improving time to optimal Staphylococcus aureus treatment using a penicillin-binding protein 2a assay

Sonia N. Rao, Sheila K. Wang, Jose Gonzalez Zamora, Amy P. Hanson, Radhika S. Polisetty, Kamaljit Singh

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

The penicillin-binding protein 2a (PBP2a) assay is a quick, accurate and inexpensive test for determining methicillin susceptibility in Staphylococcus aureus. A pre-post-study design was conducted using a PBP2a assay with and without the impact of an antimicrobial stewardship intervention to improve time to optimal therapy for methicillin-susceptible and methicillin-resistant S. aureus isolates. Our results demonstrate significantly improved time to optimal therapy and support the use of a PBP2a assay as part of an programme for all healthcare facilities, especially those with limited resources.

Original languageEnglish (US)
Article number000365
Pages (from-to)1452-1455
Number of pages4
JournalJournal of Medical Microbiology
Volume65
Issue number12
DOIs
StatePublished - Dec 2016

ASJC Scopus subject areas

  • Microbiology
  • Microbiology (medical)

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