Improving TBI lung dose calculations: Can the treatment planning system help?

Narottam Lamichhane, Matthew T. Studenski

Research output: Contribution to journalArticle

Abstract

Lung toxicity is a serious concern during total body irradiation (TBI). Therefore, evaluation of accurate dose calculation when using lung blocks is of utmost importance. Existing clinical treatment planning systems can perform the calculation but there are large inaccuracies when calculating volumetric dose at extended distances in the presence of high atomic number materials. Percent depth dose and absolute dose measurements acquired at 400 cm SSD with a cerrobend block were compared with calculated values from the Eclipse treatment planning system using AAA and Acuros. The block was simulated in 2 ways; (1) manually drawing a contour to mimic the block and (2) creating a virtual block in the accessory tray. Although the relative dose distribution was accurately calculated, larger deviations of around 50% and 40% were observed between measured depth dose and absolute dose with AAA and Acuros, respectively. Deviations were reduced by optimizing the relative electron density in the contoured block or the transmission factor in the virtual block.

Original languageEnglish (US)
Pages (from-to)168-171
Number of pages4
JournalMedical Dosimetry
Volume45
Issue number2
DOIs
StatePublished - Jun 1 2020
Externally publishedYes

Keywords

  • AAA
  • Acuros
  • Lung dose
  • Total body irradiation

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology
  • Oncology
  • Radiology Nuclear Medicine and imaging

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