Improving surgical outcomes in renal cell carcinoma involving the inferior vena cava

Javier González, Guillermo Andrés, Juan Ignacio Martínez-Salamanca, Gaetano Ciancio

Research output: Contribution to journalReview article

8 Scopus citations

Abstract

Radical nephrectomy with tumor thrombectomy remains the mainstay of treatment in renal cell carcinoma with inferior vena cava extension. Despite the rapid improvements experienced in perioperative care in recent years, this intervention still often results in significant morbidity and mortality. A deeper understanding of salient features of this complex operation provides a valuable insight into the clinical mechanisms underlying the variations observed in surgical outcomes. The 'operation profile' serves not only as a basis for making an adequate prognostic assessment, but also creates a platform from which 'innovative' strategies for improving quality and safety can be made. The present review aims to set a 'profile' for radical nephrectomy and tumor thrombectomy, and to propose a number of strategies that may reduce the complication rates of this intervention.

Original languageEnglish (US)
Pages (from-to)1373-1387
Number of pages15
JournalExpert review of anticancer therapy
Volume13
Issue number12
DOIs
StatePublished - Nov 29 2013

Keywords

  • Complications
  • Inferior vena cava
  • Morbidity
  • Mortality
  • Operation profile
  • Quality
  • Renal cell carcinoma
  • Safety
  • Surgical outcomes
  • Tumor thrombus

ASJC Scopus subject areas

  • Pharmacology (medical)
  • Oncology

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