Improving outcomes in DCDD liver transplantation: There can only be strength in numbers

D. S. Goldberg, P. L. Abt

Research output: Contribution to journalArticlepeer-review

9 Scopus citations

Abstract

In the United States, liver transplantation using donation after circulatory determination of death (DCDD) donors is challenged by persistently inferior graft survival compared with donation after neurological death (DND), along with declining rates of liver transplantation relative to the total number of DCDD donors. Advances in adult-to-adult living donor liver transplantation graft survival temporally related to the Adult-to-Adult Living Donor Liver Transplantation Cohort Study consortium suggest that a similarly focused collaborative effort may serve to stimulate evolution within DCDD liver transplantation. Without a multi-center consortium to support innovative trials, the current state of DCDD liver transplantation is unlikely to progress. The authors contend that the current state of donation after circulatory determination of death liver transplantation will not advance without a focused initiative, and herein they present arguments to support this contention.

Original languageEnglish (US)
Pages (from-to)1016-1020
Number of pages5
JournalAmerican Journal of Transplantation
Volume14
Issue number5
DOIs
StatePublished - May 2014
Externally publishedYes

Keywords

  • A2ALL
  • donor selection
  • ex vivo perfusion
  • living donor liver transplantation
  • warm ischemia

ASJC Scopus subject areas

  • Immunology and Allergy
  • Transplantation
  • Pharmacology (medical)

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