Multiple organ systems are influenced by HIV infection and many of these influences may have a direct or indirect impact upon host nutritional status. Certainly the influences upon the gastrointestinal tract have the most readily obvious consequences. Due to the influence of multiple infections, opportunistic and otherwise, along with malignancies and an enteropathy which appears to be directy related to HIV infection itself, the intake, digestion and absorption of a wide variety of nutrients is influenced by the effects of HIV infection upon the gastrointestinal tract. The effects of HIV infection upon the CNS, the lungs, the kidneys and the liver may further contribute to the deterioration of host nutritional status in HIV infection. While wasting and severe malnutrition frequently characterize the AIDS patient, it would appear that HIV patients who remain relatively asymptomatic other than persistent generalized lymphadenopathy also experience much more subtle, yet potentially significant alterations in nutritional status. As will be underscored in the second paper in this series, such alterations in host nutritional status can have significant implications for the rate and course of disease progression in HIV infection.
|Original language||English (US)|
|Number of pages||19|
|Journal||Archives of AIDS Research|
|State||Published - Dec 1 1989|
ASJC Scopus subject areas
- Immunology and Allergy