TY - JOUR
T1 - Impact of ocular surface symptoms on quality of life in a United States veterans affairs population
AU - Pouyeh, Bozorgmehr
AU - Viteri, Eduardo
AU - Feuer, William
AU - Lee, David J.
AU - Florez, Hermes
AU - Fabian, James A.
AU - Perez, Victor L.
AU - Galor, Anat
N1 - Funding Information:
All authors have completed and submitted the ICMJE Form for Disclosure of Potential Conflicts of Interest. Publication of this article was supported by a grant from the Veterans Affairs Medical Center (Dr Galor) and with unrestricted funds from Research to Prevent Blindness, New York, New York. The authors disclose the following financial relationships: A.G.: Veterans Affairs career development award >10,000; V.L.P.: consultancy fees and lecture fees, Alcon ; grant ( RO1 EY018624-01 ), Alcon, Bank of America; D.L.: grants NEI R21 EY019096 , R01OH00315 , CDC 66442T , and 1U58DP002652-01 , James and Esther King Biomedical Research grant 1KG07-33979 , Bankhead Coley 1BG06-341963 ; H.F.: NIH grant 1R18AE000049-01 and Merit review grants (VA, CSP-465 and CSP-G002 ). Involved in conception and design (A.G.), analysis and interpretation (A.G., W.F., D.J.L., H.F.), writing the article (B.P., A.G.), critical revision (A.G., W.F., D.J.L., H.F., D.C., V.L.P., J.F., E.V., B.P.), final approval (A.G., W.F., D.J.L., H.F., D.C., V.L.P., J.F., E.V., B.P.), data collection (B.P., E.V.), statistical expertise (A.G., W.F., D.J.L., H.F.), and literature search (A.G.). The VA ophthalmology service initiated this study as a quality improvement project. Miami VAMC Institutional Review Board review and approval was later obtained to perform a chart review and link patient data to the questionnaires. The study was conducted in accordance with the principles of the Declaration of Helsinki. The authors would like to acknowledge Ehsan Mozayan for his help with entering the questionnaire scores into the database.
PY - 2012/6
Y1 - 2012/6
N2 - Purpose: To evaluate the impact of ocular surface symptoms on quality of life in a veteran population receiving eye care services. Design: Cross-sectional survey study. Methods: setting: Miami Veterans Affairs Medical Center (VAMC). patient population: Patients seen at the eye clinic between June and August 2010 were asked to fill out the Dry Eye Questionnaire 5 (DEQ5) and the Impact of Dry Eye on Everyday Life (IDEEL) questionnaire. main outcome measures: Correlation between ocular surface symptoms and functionality. Results: Four hundred eighty-nine patients elected to fill out the DEQ5 questionnaire (36% response rate). The mean age of respondents was 66 years (standard deviation 12). Ninety-four percent were male; 62% were white and 37% were black. Using the DEQ5 as a surrogate measure of ocular surface symptoms, 65% of respondents reported at least mild ocular surface symptoms (DEQ5 <6) and 27% of them reported severe symptoms (DEQ5 <12). Black subjects had a 2-fold increased risk of severe symptoms compared to white subjects (odds ratio 2.06, 95% confidence interval 1.33-3.19). Several medications were associated with a significantly increased risk of severe symptoms, including glaucoma medications (1.7-fold increase), antidepressants (2.3-fold increase), and antihistamines (2.1-fold increase). There was an inverse correlation between DEQ5 and IDEEL scores with regard to ability to perform activities of daily living (n = 391, r = -0.54, P <.001), emotional well-being (n = 386, r = -0.63, P <.001), and the ability to work (n = 205, r = -0.57, P <.001). Fifty percent of patients with severe symptoms had documentation that their symptoms were addressed during the visit. Conclusion: Severe ocular surface symptoms reduce the quality of life of Miami VAMC veterans. Eye care professionals should be vigilant in eliciting ocular surface complaints from their patients.
AB - Purpose: To evaluate the impact of ocular surface symptoms on quality of life in a veteran population receiving eye care services. Design: Cross-sectional survey study. Methods: setting: Miami Veterans Affairs Medical Center (VAMC). patient population: Patients seen at the eye clinic between June and August 2010 were asked to fill out the Dry Eye Questionnaire 5 (DEQ5) and the Impact of Dry Eye on Everyday Life (IDEEL) questionnaire. main outcome measures: Correlation between ocular surface symptoms and functionality. Results: Four hundred eighty-nine patients elected to fill out the DEQ5 questionnaire (36% response rate). The mean age of respondents was 66 years (standard deviation 12). Ninety-four percent were male; 62% were white and 37% were black. Using the DEQ5 as a surrogate measure of ocular surface symptoms, 65% of respondents reported at least mild ocular surface symptoms (DEQ5 <6) and 27% of them reported severe symptoms (DEQ5 <12). Black subjects had a 2-fold increased risk of severe symptoms compared to white subjects (odds ratio 2.06, 95% confidence interval 1.33-3.19). Several medications were associated with a significantly increased risk of severe symptoms, including glaucoma medications (1.7-fold increase), antidepressants (2.3-fold increase), and antihistamines (2.1-fold increase). There was an inverse correlation between DEQ5 and IDEEL scores with regard to ability to perform activities of daily living (n = 391, r = -0.54, P <.001), emotional well-being (n = 386, r = -0.63, P <.001), and the ability to work (n = 205, r = -0.57, P <.001). Fifty percent of patients with severe symptoms had documentation that their symptoms were addressed during the visit. Conclusion: Severe ocular surface symptoms reduce the quality of life of Miami VAMC veterans. Eye care professionals should be vigilant in eliciting ocular surface complaints from their patients.
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U2 - 10.1016/j.ajo.2011.11.030
DO - 10.1016/j.ajo.2011.11.030
M3 - Article
C2 - 22330309
AN - SCOPUS:84862783754
VL - 153
SP - 1061-1066.e3
JO - American Journal of Ophthalmology
JF - American Journal of Ophthalmology
SN - 0002-9394
IS - 6
ER -