Immunoreactive prekeratin in brenner tumors of the ovary

Parvin Ganjei, Mehrdad Nadji, Neal S. Penneys, Hervy E. Averette, Azorides R. Morales

Research output: Contribution to journalArticle

13 Scopus citations

Abstract

In an attempt to further characterize benign, proliferating, and malignant Brenner tumors, immunoperoxidase staining for prekeratin was undertaken in a group of these neoplasms as well as in a variety of histologically different tumors of the ovary. All Brenner tumors reacted positively for prekeratin, whereas none of the other epithelial or sex cord-stromal tumors of the ovary stained. On the basis of these findings, we conclude that prekeratin might be a useful marker for differentiating malignant Brenner tumors from histologically similar, poorly differentiated ovarian neoplasms.

Original languageEnglish (US)
Pages (from-to)353-358
Number of pages6
JournalInternational Journal of Gynecological Pathology
Volume1
Issue number4
DOIs
StatePublished - Jan 1983

Keywords

  • Brenner tumors
  • Immunoperoxidase staining
  • Ovary
  • Prekeratin

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Obstetrics and Gynecology

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