Immunologic mechanisms in experimental encephalomyelitis in nonhuman primates

P. O. Behan, M. W. Kies, R. P. Lisak, William Sheremata, J. B. Lamarche

Research output: Contribution to journalArticle

32 Citations (Scopus)

Abstract

Experimental allergic encephalomyelitis was induced in large rhesus monkeys by immunizing them with homologous and heterologous myelin basic proteins in different adjuvants. Two clinically and pathologically different types of disease, ordinary and hyperacute, were produced. In both types cell mediated hypersensitivity was demonstrated to a variety of myelin basic proteins from different species by in vivo and in vitro techniques. Humoral antibody to homologous myelin basic protein could only be found in the fulminant hyperacute form.

Original languageEnglish
Pages (from-to)4-9
Number of pages6
JournalArchives of Neurology
Volume29
Issue number1
StatePublished - Dec 1 1973
Externally publishedYes

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Encephalomyelitis
Myelin Basic Protein
Primates
Autoimmune Experimental Encephalomyelitis
Macaca mulatta
Hypersensitivity
Antibodies
Nonhuman Primate
Protein

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Behan, P. O., Kies, M. W., Lisak, R. P., Sheremata, W., & Lamarche, J. B. (1973). Immunologic mechanisms in experimental encephalomyelitis in nonhuman primates. Archives of Neurology, 29(1), 4-9.

Immunologic mechanisms in experimental encephalomyelitis in nonhuman primates. / Behan, P. O.; Kies, M. W.; Lisak, R. P.; Sheremata, William; Lamarche, J. B.

In: Archives of Neurology, Vol. 29, No. 1, 01.12.1973, p. 4-9.

Research output: Contribution to journalArticle

Behan, PO, Kies, MW, Lisak, RP, Sheremata, W & Lamarche, JB 1973, 'Immunologic mechanisms in experimental encephalomyelitis in nonhuman primates', Archives of Neurology, vol. 29, no. 1, pp. 4-9.
Behan PO, Kies MW, Lisak RP, Sheremata W, Lamarche JB. Immunologic mechanisms in experimental encephalomyelitis in nonhuman primates. Archives of Neurology. 1973 Dec 1;29(1):4-9.
Behan, P. O. ; Kies, M. W. ; Lisak, R. P. ; Sheremata, William ; Lamarche, J. B. / Immunologic mechanisms in experimental encephalomyelitis in nonhuman primates. In: Archives of Neurology. 1973 ; Vol. 29, No. 1. pp. 4-9.
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