Vulvar neoplasms include lesions which occur most often in the anogenital region. These neoplasms are readily accessible to inspection, palpation, and direct biopsy. In most instances, the physician's discovery of a lesion leads to excision of part or all of the tumor. While the majority of vulvar neoplasms present no diagnostic problem histologically, in some instances it may be difficult to differentiate one type of tumor from another with routine stains; furthermore, histogenesis of some of these neoplasms remains controversial. In this review, the authors examine the value of the immunoperoxidase technique in the histogenetic assessment of a number of vulvar neoplasms and its pracital application in the differential diagnosis of some look-alike lesions in that region.
ASJC Scopus subject areas
- Pathology and Forensic Medicine
- Obstetrics and Gynecology