Immunohistochemical localization of somatostatin in endocrine cells of the rat stomach

R. Leclerc, G. Pelletier, R. Puviani, A. Arimura, Andrew V Schally

Research output: Contribution to journalArticle

22 Citations (Scopus)

Abstract

Using an immunohistochemical technique involving unlabeled antibody and the peroxidaseanti-peroxidase complex, we have localized somatostatin (or growth hormone-release inhibiting hormone), a hypothalamic hormone which can also inhibit gastrin secretion, in the rat stomach. Somatostatin was found to be present in a few cells in the mucosa of the pyloric antrum. These cells are characterized by the presence of secretory granules of about 150-250 nm in diameter and are probably endocrine cells.

Original languageEnglish
Pages (from-to)257-261
Number of pages5
JournalMolecular and Cellular Endocrinology
Volume4
Issue number4
DOIs
StatePublished - Jan 1 1976
Externally publishedYes

Fingerprint

Endocrine Cells
Somatostatin
Rats
Stomach
Cells
Hypothalamic Hormones
Pyloric Antrum
Gastrins
Secretory Vesicles
Peroxidase
Growth Hormone
Mucous Membrane
Hormones
Antibodies

Keywords

  • gastrin
  • hypothalamus
  • immunohistochemistry
  • stomatostatin

ASJC Scopus subject areas

  • Endocrinology
  • Endocrinology, Diabetes and Metabolism

Cite this

Immunohistochemical localization of somatostatin in endocrine cells of the rat stomach. / Leclerc, R.; Pelletier, G.; Puviani, R.; Arimura, A.; Schally, Andrew V.

In: Molecular and Cellular Endocrinology, Vol. 4, No. 4, 01.01.1976, p. 257-261.

Research output: Contribution to journalArticle

Leclerc, R. ; Pelletier, G. ; Puviani, R. ; Arimura, A. ; Schally, Andrew V. / Immunohistochemical localization of somatostatin in endocrine cells of the rat stomach. In: Molecular and Cellular Endocrinology. 1976 ; Vol. 4, No. 4. pp. 257-261.
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