Immunoglobulins, cognitive status and duration of illness in alzheimer's disease

Donna Cohen, Carl Eisdorfer, Patricia Prinz, James Leverenz, Mark Davis

Research output: Contribution to journalArticle

2 Scopus citations

Abstract

Immunologic changes have been reported in the dementing illnesses of mid and late life. The results of two studies of drug-free males meeting research diagnostic criteria for primary neuronal degeneration of the Alzheimer's type suggest that serum IgG levels decrease with the progression of dementia. Serum IgG levels were inversely correlated with duration of illness and the levels of psychiatric symptomatology. Performance on the mini-mental status examination was positively associated with serum IgG concentrations.

Original languageEnglish (US)
Pages (from-to)165-168
Number of pages4
JournalNeurobiology of aging
Volume1
Issue number2
DOIs
StatePublished - Jan 1 1980

Keywords

  • Alzheimer's disease
  • Cognitive status
  • Duration of illness
  • Immunoglobulins

ASJC Scopus subject areas

  • Clinical Neurology
  • Biological Psychiatry
  • Developmental Neuroscience
  • Neurology
  • Psychology(all)

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