Immunoglobulins, cognitive status and duration of illness in alzheimer's disease

Donna Cohen; Carl Eisdorfer; Patricia Prinz; James Leverenz; Mark Davis

doi:10.1016/0197-4580(80)90011-1

Immunoglobulins, cognitive status and duration of illness in alzheimer's disease

Donna Cohen, Carl Eisdorfer, Patricia Prinz, James Leverenz, Mark Davis

Psychiatry & Behavioral Sciences

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

Immunologic changes have been reported in the dementing illnesses of mid and late life. The results of two studies of drug-free males meeting research diagnostic criteria for primary neuronal degeneration of the Alzheimer's type suggest that serum IgG levels decrease with the progression of dementia. Serum IgG levels were inversely correlated with duration of illness and the levels of psychiatric symptomatology. Performance on the mini-mental status examination was positively associated with serum IgG concentrations.

Original language	English (US)
Pages (from-to)	165-168
Number of pages	4
Journal	Neurobiology of aging
Volume	1
Issue number	2
DOIs	https://doi.org/10.1016/0197-4580(80)90011-1
State	Published - Jan 1 1980

Keywords

Alzheimer's disease
Cognitive status
Duration of illness
Immunoglobulins

ASJC Scopus subject areas

Clinical Neurology
Biological Psychiatry
Developmental Neuroscience
Neurology
Psychology(all)

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10.1016/0197-4580(80)90011-1

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abstract = "Immunologic changes have been reported in the dementing illnesses of mid and late life. The results of two studies of drug-free males meeting research diagnostic criteria for primary neuronal degeneration of the Alzheimer's type suggest that serum IgG levels decrease with the progression of dementia. Serum IgG levels were inversely correlated with duration of illness and the levels of psychiatric symptomatology. Performance on the mini-mental status examination was positively associated with serum IgG concentrations.",

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AU - Cohen, Donna

AU - Eisdorfer, Carl

AU - Prinz, Patricia

AU - Leverenz, James

AU - Davis, Mark

PY - 1980/1/1

Y1 - 1980/1/1

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AB - Immunologic changes have been reported in the dementing illnesses of mid and late life. The results of two studies of drug-free males meeting research diagnostic criteria for primary neuronal degeneration of the Alzheimer's type suggest that serum IgG levels decrease with the progression of dementia. Serum IgG levels were inversely correlated with duration of illness and the levels of psychiatric symptomatology. Performance on the mini-mental status examination was positively associated with serum IgG concentrations.

KW - Alzheimer's disease

KW - Cognitive status

KW - Duration of illness

KW - Immunoglobulins

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Immunoglobulins, cognitive status and duration of illness in alzheimer's disease

Abstract

Keywords

ASJC Scopus subject areas

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