Abstract
Immunologic changes have been reported in the dementing illnesses of mid and late life. The results of two studies of drug-free males meeting research diagnostic criteria for primary neuronal degeneration of the Alzheimer's type suggest that serum IgG levels decrease with the progression of dementia. Serum IgG levels were inversely correlated with duration of illness and the levels of psychiatric symptomatology. Performance on the mini-mental status examination was positively associated with serum IgG concentrations.
| Original language | English |
|---|---|
| Pages (from-to) | 165-168 |
| Number of pages | 4 |
| Journal | Neurobiology of Aging |
| Volume | 1 |
| Issue number | 2 |
| DOIs | |
| State | Published - Jan 1 1980 |
| Externally published | Yes |
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Keywords
- Alzheimer's disease
- Cognitive status
- Duration of illness
- Immunoglobulins
ASJC Scopus subject areas
- Clinical Neurology
- Biological Psychiatry
- Developmental Neuroscience
- Neurology
- Psychology(all)
Cite this
Immunoglobulins, cognitive status and duration of illness in alzheimer's disease. / Cohen, Donna; Eisdorfer, Carl; Prinz, Patricia; Leverenz, James; Davis, Mark.
In: Neurobiology of Aging, Vol. 1, No. 2, 01.01.1980, p. 165-168.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Immunoglobulins, cognitive status and duration of illness in alzheimer's disease
AU - Cohen, Donna
AU - Eisdorfer, Carl
AU - Prinz, Patricia
AU - Leverenz, James
AU - Davis, Mark
PY - 1980/1/1
Y1 - 1980/1/1
N2 - Immunologic changes have been reported in the dementing illnesses of mid and late life. The results of two studies of drug-free males meeting research diagnostic criteria for primary neuronal degeneration of the Alzheimer's type suggest that serum IgG levels decrease with the progression of dementia. Serum IgG levels were inversely correlated with duration of illness and the levels of psychiatric symptomatology. Performance on the mini-mental status examination was positively associated with serum IgG concentrations.
AB - Immunologic changes have been reported in the dementing illnesses of mid and late life. The results of two studies of drug-free males meeting research diagnostic criteria for primary neuronal degeneration of the Alzheimer's type suggest that serum IgG levels decrease with the progression of dementia. Serum IgG levels were inversely correlated with duration of illness and the levels of psychiatric symptomatology. Performance on the mini-mental status examination was positively associated with serum IgG concentrations.
KW - Alzheimer's disease
KW - Cognitive status
KW - Duration of illness
KW - Immunoglobulins
UR - http://www.scopus.com/inward/record.url?scp=0019293739&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0019293739&partnerID=8YFLogxK
U2 - 10.1016/0197-4580(80)90011-1
DO - 10.1016/0197-4580(80)90011-1
M3 - Article
VL - 1
SP - 165
EP - 168
JO - Neurobiology of Aging
JF - Neurobiology of Aging
SN - 0197-4580
IS - 2
ER -