Abstract
The cotton-top tamarin (Saguinus oedipus) has been widely used as a model in biomedical research to study the pathogenesis of certain human diseases. 1 The reason for using this particular species stems, in part, from its extreme susceptibility to a variety of viruses. S. oedipus develops fatal lymphoproliferative syndromes following infections with Epstein-Barr virus (EBV) 2 and Herpesvirus saimiri, 3 The cotton-top tamarin also appears to be far more susceptible to retrovirus-induced sarcomas and fatal measle virus infections than other species. 4, 5 Additionally, as many as 60% of captive S. oedipus spontaneously develop ulcerative colitis and 15% develop adenocarcinoma of the colon.
| Original language | English (US) |
|---|---|
| Title of host publication | A Primate Model for the Study of Colitis and Colonic Carcinoma the Cotton-Top Tamarin (Saguinus oedipus) |
| Publisher | CRC Press |
| Pages | 295-308 |
| Number of pages | 14 |
| ISBN (Electronic) | 9781351077866 |
| ISBN (Print) | 0849353637, 9781315890319 |
| DOIs | |
| State | Published - Jan 1 2018 |
| Externally published | Yes |
ASJC Scopus subject areas
- Medicine(all)
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Cite this
Watkins, D., & Letvin, N. L. (2018). Immunobiology of the cotton-top tamarin. In A Primate Model for the Study of Colitis and Colonic Carcinoma the Cotton-Top Tamarin (Saguinus oedipus) (pp. 295-308). CRC Press. https://doi.org/10.1201/9781351069410