Immunobiology of the cotton-top tamarin

David Watkins; Norman L. Letvin

doi:10.1201/9781351069410

Immunobiology of the cotton-top tamarin

David Watkins, Norman L. Letvin

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

The cotton-top tamarin (Saguinus oedipus) has been widely used as a model in biomedical research to study the pathogenesis of certain human diseases. 1 The reason for using this particular species stems, in part, from its extreme susceptibility to a variety of viruses. S. oedipus develops fatal lymphoproliferative syndromes following infections with Epstein-Barr virus (EBV) 2 and Herpesvirus saimiri, 3 The cotton-top tamarin also appears to be far more susceptible to retrovirus-induced sarcomas and fatal measle virus infections than other species. 4, 5 Additionally, as many as 60% of captive S. oedipus spontaneously develop ulcerative colitis and 15% develop adenocarcinoma of the colon.

Original language	English (US)
Title of host publication	A Primate Model for the Study of Colitis and Colonic Carcinoma the Cotton-Top Tamarin (Saguinus oedipus)
Publisher	CRC Press
Pages	295-308
Number of pages	14
ISBN (Electronic)	9781351077866
ISBN (Print)	0849353637, 9781315890319
DOIs	https://doi.org/10.1201/9781351069410
State	Published - Jan 1 2018
Externally published	Yes

ASJC Scopus subject areas

Medicine(all)

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1201/9781351069410

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Immunobiology of the cotton-top tamarin

Abstract

ASJC Scopus subject areas

UN SDGs

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