Immobilized ligands for cell and tissue interactions

J. A. Hubbell, P. D. Drumheller

Research output: Contribution to journalConference article

Abstract

The interaction of adhesion receptors with their protein ligands can be localized to small domains, called the cell-binding domain, on the surface of the protein. The receptor-binding activity of the cell-binding domain can be mimicked by short oligopeptides of the same or related sequence as that of the cell-binding domain. These oligopeptides have been incorporated into the surfaces of polymeric biomaterials, resulting in surfaces for the cells bear receptors directly.

Original languageEnglish (US)
Pages (from-to)A19
JournalArtificial Cells, Blood Substitutes, and Immobilization Biotechnology
Volume22
Issue number5
StatePublished - Nov 1 1994
EventProceedings of the 11th Congress of the International Society for Artificial Cells, Blood Substitutes and Immobilization Biotechnology, (ISABI) - Boston, MA, USA
Duration: Jul 24 1994Jul 27 1994

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ASJC Scopus subject areas

  • Biotechnology
  • Biomedical Engineering

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