The interaction of adhesion receptors with their protein ligands can be localized to small domains, called the cell-binding domain, on the surface of the protein. The receptor-binding activity of the cell-binding domain can be mimicked by short oligopeptides of the same or related sequence as that of the cell-binding domain. These oligopeptides have been incorporated into the surfaces of polymeric biomaterials, resulting in surfaces for the cells bear receptors directly.
|Original language||English (US)|
|Journal||Artificial Cells, Blood Substitutes, and Immobilization Biotechnology|
|State||Published - Nov 1 1994|
|Event||Proceedings of the 11th Congress of the International Society for Artificial Cells, Blood Substitutes and Immobilization Biotechnology, (ISABI) - Boston, MA, USA|
Duration: Jul 24 1994 → Jul 27 1994
ASJC Scopus subject areas
- Biomedical Engineering