Immobilization of Quantum Dots in the Photo-Cross-Linked Poly(ethylene glycol)-Based Hydrogel

Kerim M. Gattás-Asfura, Yujun Zheng, Miodrag Micic, Michael J. Snedaker, Xiaojun Ji, Guodong Sui, Jhony Orbulescu, Fotios M Andreopoulos, Si M. Pham, Chongmin Wang, Roger Leblanc

Research output: Contribution to journalArticle

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Abstract

An inorganic/organic composite hybrid nano-system has been successfully synthesized in which nanocrystalline quantum dots (QDs) were effectively immobilized within a photo-cross-linked polyethylene glycol) (PEG) hydrogel. The immobilization of 3.5-6.0 nm CdTe and 2.0-3.5 nm CdSe QDs within the PEG hydrogel network has been shown to be effective through utilization of physical trapping. These QD-immobilized gel systems demonstrated luminescence characteristics unique to semiconductor QD nanocrystals. Controlled particle extraction from the PEG hydrogel matrix may be possible via a photocleavage process. The solubility property of QDs was controlled through surface functionalization. It is envisioned that the unique photophysical properties of this new material can be utilized as a convenient signal transducer for chemo-/bio-sensing. A promising application of the described QD/PEG-NC hybrid system may be in the fields of fluoroimmunoassay and as a monitoring system for drug delivery and wound healing.

Original languageEnglish
Pages (from-to)10464-10469
Number of pages6
JournalJournal of Physical Chemistry B
Volume107
Issue number38
StatePublished - Sep 25 2003

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Hydrogel
immobilization
Hydrogels
Polyethylene glycols
Semiconductor quantum dots
glycols
ethylene
quantum dots
hybrid composites
wound healing
healing
Hybrid systems
Drug delivery
Nanocrystals
Particles (particulate matter)
Luminescence
polyethylenes
Transducers
delivery
nanocrystals

ASJC Scopus subject areas

  • Physical and Theoretical Chemistry

Cite this

Gattás-Asfura, K. M., Zheng, Y., Micic, M., Snedaker, M. J., Ji, X., Sui, G., ... Leblanc, R. (2003). Immobilization of Quantum Dots in the Photo-Cross-Linked Poly(ethylene glycol)-Based Hydrogel. Journal of Physical Chemistry B, 107(38), 10464-10469.

Immobilization of Quantum Dots in the Photo-Cross-Linked Poly(ethylene glycol)-Based Hydrogel. / Gattás-Asfura, Kerim M.; Zheng, Yujun; Micic, Miodrag; Snedaker, Michael J.; Ji, Xiaojun; Sui, Guodong; Orbulescu, Jhony; Andreopoulos, Fotios M; Pham, Si M.; Wang, Chongmin; Leblanc, Roger.

In: Journal of Physical Chemistry B, Vol. 107, No. 38, 25.09.2003, p. 10464-10469.

Research output: Contribution to journalArticle

Gattás-Asfura, KM, Zheng, Y, Micic, M, Snedaker, MJ, Ji, X, Sui, G, Orbulescu, J, Andreopoulos, FM, Pham, SM, Wang, C & Leblanc, R 2003, 'Immobilization of Quantum Dots in the Photo-Cross-Linked Poly(ethylene glycol)-Based Hydrogel', Journal of Physical Chemistry B, vol. 107, no. 38, pp. 10464-10469.
Gattás-Asfura KM, Zheng Y, Micic M, Snedaker MJ, Ji X, Sui G et al. Immobilization of Quantum Dots in the Photo-Cross-Linked Poly(ethylene glycol)-Based Hydrogel. Journal of Physical Chemistry B. 2003 Sep 25;107(38):10464-10469.
Gattás-Asfura, Kerim M. ; Zheng, Yujun ; Micic, Miodrag ; Snedaker, Michael J. ; Ji, Xiaojun ; Sui, Guodong ; Orbulescu, Jhony ; Andreopoulos, Fotios M ; Pham, Si M. ; Wang, Chongmin ; Leblanc, Roger. / Immobilization of Quantum Dots in the Photo-Cross-Linked Poly(ethylene glycol)-Based Hydrogel. In: Journal of Physical Chemistry B. 2003 ; Vol. 107, No. 38. pp. 10464-10469.
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