IgCAMs: Bidirectional signals underlying neurite growth

Hiroyuki Kamiguchi, Vance Lemmon

Research output: Contribution to journalReview articlepeer-review

86 Scopus citations


Understanding how immunoglobulin superfamily cell adhesion molecules (IgCAMs) regulate nervous system development has lagged behind studies on integrins and cadherins. The recent characterization of IgCAM structures combined with cell biological studies on protein-protein interactions and membrane targeting/trafficking demonstrate that IgCAMs interact in exceedingly complex ways to regulate axonal growth and pathfinding.

Original languageEnglish (US)
Pages (from-to)598-605
Number of pages8
JournalCurrent Opinion in Cell Biology
Issue number5
StatePublished - 2000
Externally publishedYes

ASJC Scopus subject areas

  • Cell Biology


Dive into the research topics of 'IgCAMs: Bidirectional signals underlying neurite growth'. Together they form a unique fingerprint.

Cite this