IgCAMs

Bidirectional signals underlying neurite growth

Hiroyuki Kamiguchi, Vance Lemmon

Research output: Contribution to journalArticle

85 Citations (Scopus)

Abstract

Understanding how immunoglobulin superfamily cell adhesion molecules (IgCAMs) regulate nervous system development has lagged behind studies on integrins and cadherins. The recent characterization of IgCAM structures combined with cell biological studies on protein-protein interactions and membrane targeting/trafficking demonstrate that IgCAMs interact in exceedingly complex ways to regulate axonal growth and pathfinding.

Original languageEnglish
Pages (from-to)598-605
Number of pages8
JournalCurrent Opinion in Cell Biology
Volume12
Issue number5
DOIs
StatePublished - Sep 28 2000
Externally publishedYes

Fingerprint

Cell Adhesion Molecules
Neurites
Immunoglobulins
Growth
Cadherins
Integrins
Nervous System
Membrane Proteins
Proteins

ASJC Scopus subject areas

  • Cell Biology

Cite this

IgCAMs : Bidirectional signals underlying neurite growth. / Kamiguchi, Hiroyuki; Lemmon, Vance.

In: Current Opinion in Cell Biology, Vol. 12, No. 5, 28.09.2000, p. 598-605.

Research output: Contribution to journalArticle

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