IgCAMs: Bidirectional signals underlying neurite growth

Hiroyuki Kamiguchi; Vance Lemmon

doi:10.1016/S0955-0674(00)00138-1

IgCAMs: Bidirectional signals underlying neurite growth

Hiroyuki Kamiguchi, Vance Lemmon

Neurological Surgery

Research output: Contribution to journal › Review article

85 Scopus citations

Abstract

Understanding how immunoglobulin superfamily cell adhesion molecules (IgCAMs) regulate nervous system development has lagged behind studies on integrins and cadherins. The recent characterization of IgCAM structures combined with cell biological studies on protein-protein interactions and membrane targeting/trafficking demonstrate that IgCAMs interact in exceedingly complex ways to regulate axonal growth and pathfinding.

Original language	English (US)
Pages (from-to)	598-605
Number of pages	8
Journal	Current Opinion in Cell Biology
Volume	12
Issue number	5
DOIs	https://doi.org/10.1016/S0955-0674(00)00138-1
State	Published - Jan 1 2000

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ASJC Scopus subject areas

Cell Biology

Cite this

Kamiguchi, H., & Lemmon, V. (2000). IgCAMs: Bidirectional signals underlying neurite growth. Current Opinion in Cell Biology, 12(5), 598-605. https://doi.org/10.1016/S0955-0674(00)00138-1

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Access to Document

10.1016/S0955-0674(00)00138-1