Idiopathic atrophy of the nails: Clinical and pathological study of 2 cases

A. Tosti, B. M. Piraccini, P. A. Fcmti, F. Bardazzi, A. Di Landro

Research output: Contribution to journalArticlepeer-review

15 Scopus citations


Background: Whether idiopathic atrophy of the nails (IAN) should be considered a separate entity or a clinical variant of nail lichen planus is still controversial. Objective: We report here the pathological study of patients with IAN. Methods: Our patients had similar clinical features consisting of severe nail atrophy with and without pterygium. Results: The nail matrix architecture was markedly deformed with complete disappearance of tile keratogenous zone that was replaced by a 3- to 10-cell-thick granular layer. Conclusion: The hypothesis that IAN is an acute and self-limited variety of lichen planus is still the most presumable. Even though this hypothesis can not be definitely proven, it is nevertheless not excluded by the clinical and pathological findings of our cases.

Original languageEnglish (US)
Pages (from-to)116-118
Number of pages3
Issue number2
StatePublished - Jan 1 1995
Externally publishedYes


  • Idiopathic nail atrophy
  • Lichen planus
  • Nail matrix hypergranulosis
  • Pterygium

ASJC Scopus subject areas

  • Dermatology


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