Ichthyosis Follicularis in Two Girls: An Autosomal Dominant Disorder

Marti J. Rothe, Darryl S. Weiss, Barry H. Dubner, Jay M. Weitzner, Anne W. Lucky, Lawrence Schachner

Research output: Contribution to journalArticle

19 Scopus citations

Abstract

Ichthyosis follicularis (IF) is a rare disorder of keratinization that has been described primarily in males and proposed as a possible X-linked disorder. We report two black girls with nonscarring alopecia; photophobia; follicular hyperkeratoses; hyperkeratosis of the extensor aspects of the hands, knees, and elbows; fixed, erythematous, perineal plaques; and angular cheilitis who seem to fit the clinical criteria for IF. One girl also had gingival hypertrophy and a hearing deficit. One child's father had identical symptoms. We propose that these girls may have a variant of IF that is inherited as an autosomal dominant trait.

Original languageEnglish (US)
Pages (from-to)287-292
Number of pages6
JournalPediatric Dermatology
Volume7
Issue number4
DOIs
StatePublished - Dec 1990

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Dermatology

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