Ichthyosis follicularis in two girls: An autosomal dominant disorder

M. J. Rothe, D. S. Weiss, B. H. Dubner, J. M. Weitzner, A. W. Lucky, Lawrence A Schachner

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

Ichthyosis follicularis (IF) is a rare disorder of keratinization that has been described primarily in males and proposed as a possible X-linked disorder. We report two black girls with nonscarring alopecia; photophobia; follicular hyperkeratoses; hyperkeratosis of the extensor aspects of the hands, knees, and elbows; fixed, erythematous, perineal plaques; and angular cheilitis who seem to fit the clinical criteria for IF. One girl also had gingival hypertrophy and a hearing deficit. One child's father had identical symptoms. We propose that these girls may have a variant of IF that is inherited as an autosomal dominant trait.

Original languageEnglish
Pages (from-to)287-292
Number of pages6
JournalPediatric Dermatology
Volume7
Issue number4
StatePublished - Dec 1 1990

Fingerprint

Ichthyosis
Gingival Hypertrophy
Cheilitis
Photophobia
Alopecia
Elbow
Fathers
Hearing
Knee
Hand

ASJC Scopus subject areas

  • Dermatology
  • Pediatrics, Perinatology, and Child Health

Cite this

Rothe, M. J., Weiss, D. S., Dubner, B. H., Weitzner, J. M., Lucky, A. W., & Schachner, L. A. (1990). Ichthyosis follicularis in two girls: An autosomal dominant disorder. Pediatric Dermatology, 7(4), 287-292.

Ichthyosis follicularis in two girls : An autosomal dominant disorder. / Rothe, M. J.; Weiss, D. S.; Dubner, B. H.; Weitzner, J. M.; Lucky, A. W.; Schachner, Lawrence A.

In: Pediatric Dermatology, Vol. 7, No. 4, 01.12.1990, p. 287-292.

Research output: Contribution to journalArticle

Rothe, MJ, Weiss, DS, Dubner, BH, Weitzner, JM, Lucky, AW & Schachner, LA 1990, 'Ichthyosis follicularis in two girls: An autosomal dominant disorder', Pediatric Dermatology, vol. 7, no. 4, pp. 287-292.
Rothe MJ, Weiss DS, Dubner BH, Weitzner JM, Lucky AW, Schachner LA. Ichthyosis follicularis in two girls: An autosomal dominant disorder. Pediatric Dermatology. 1990 Dec 1;7(4):287-292.
Rothe, M. J. ; Weiss, D. S. ; Dubner, B. H. ; Weitzner, J. M. ; Lucky, A. W. ; Schachner, Lawrence A. / Ichthyosis follicularis in two girls : An autosomal dominant disorder. In: Pediatric Dermatology. 1990 ; Vol. 7, No. 4. pp. 287-292.
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