Ibotenic acid lesions in the medial geniculate region prevent the acquisition of differential Pavlovian conditioning of bradycardia to acoustic stimuli in rabbits

Theodore W. Jarrell, Lizabeth M. Romanski, Christopher G. Gentile, Philip M. McCabe, Neil Schneiderman

Research output: Contribution to journalArticle

29 Scopus citations

Abstract

The present study examined the effect of ibotenic acid lesions in the medial portion of the medial geniculate nucleus (mMGN) on differential heart rate (HR) conditioning to acoustic stimuli in rabbits. Lesions in mMGN prevented the acquisition of differential HR conditioned responses but not bradycardiac responses to the conditioned stimuli. The data suggest that cells in this region play an important role in the discriminative component of HR conditioning.

Original languageEnglish (US)
Pages (from-to)199-203
Number of pages5
JournalBrain Research
Volume382
Issue number1
DOIs
StatePublished - Sep 10 1986

Keywords

  • differential Pavlovian conditioning
  • heart rate
  • medial geniculate nucleus
  • rabbit

ASJC Scopus subject areas

  • Developmental Biology
  • Molecular Biology
  • Clinical Neurology
  • Neuroscience(all)

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