Hypothermia and rewarming induced by surface and He O2 inhalate temperature control

A. V. Beran, K. G. Proctor, D. R. Sperling

Research output: Contribution to journalArticlepeer-review

4 Scopus citations


Hypothermia and rewarming were induced by a combination of temperature controlled surface and inhalate methods in rabbits. To facilitate respiratory heat exchange, inhalate respiratory tract temperature and humidity gradients and thermal conductivity were increased. In addition, the upper respiratory tract was bypassed by an endotracheal tube. To aid in maintaining satisfactory circulatory dynamics, hypercapnia and hypoxia were induced. The combined surface and inhalate method produced a markedly more effective rate of cooling than surface temperature controlled method alone. Animals survived core temperatures as low as 20.9°C with no complications. The noninvasive simplicity of this method suggests its potential applicability in many clinical situations.

Original languageEnglish (US)
Pages (from-to)337-340
Number of pages4
JournalJournal of applied physiology
Issue number2
StatePublished - Jan 1 1975
Externally publishedYes

ASJC Scopus subject areas

  • Physiology
  • Physiology (medical)


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