Hyponatremia and central pontine myelinolysis

Patricia J. Burcar, Michael D. Norenberg, Philip R. Yarnell

Research output: Contribution to journalArticlepeer-review

99 Scopus citations


The autopsy findings in a patient with severe hyponatremia showing central pontine myelinolysis are reported. Review of other patients with central pontine myelinolysis and of those described in the English literature to date disclosed that 61% had documented hyponatremia. While the exact mechanism involving hyponatremia and central pontine myelinolysis is not explained, a circumstantial relation is apparent. In this paper this relation is brought to the fore and the possibility is discussed to consider a central pontine myelinolysis in any patient with hyponatremia and neurologic dysfunction.

Original languageEnglish (US)
Pages (from-to)223-226
Number of pages4
Issue number3
StatePublished - Mar 1977
Externally publishedYes

ASJC Scopus subject areas

  • Clinical Neurology


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