Hypogonadism and Testosterone Therapy: Associations With Cardiovascular Risk

Avinash Maganty, E. Charles Osterberg, Ranjith Ramasamy

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Testosterone replacement therapy (TRT) use is increasing, primarily in men with symptomatic hypogonadism. There are many benefits associated with TRT use, including improved sexual function, improved bone mineral density, and increased free fat mass and strength. As TRT use increases, its role on cardiovascular health must be explored. While previous evidence identified no adverse cardiovascular risks associated with TRT use, more recent studies suggest that there may be an associated risk, especially in elderly men and younger men with cardiac disease. Care must be taken with TRT use in these groups of men by careful monitoring for cardiac dysfunction. While testosterone therapy has many benefits and may generally be well tolerated, those prescribing the therapy must be cognizant of the potential adverse cardiovascular risks and advise men on the potential risks versus benefits.

Original languageEnglish (US)
Pages (from-to)340-344
Number of pages5
JournalAmerican Journal of Men's Health
Volume9
Issue number4
DOIs
StatePublished - Jul 19 2015
Externally publishedYes

Fingerprint

Hypogonadism
Testosterone
Therapeutics
Bone Density
Heart Diseases
Fats
monitoring
Disease
Health
health
evidence

Keywords

  • cardiovascular risk
  • testosterone replacement therapy (TRT)

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health
  • Health(social science)

Cite this

Hypogonadism and Testosterone Therapy : Associations With Cardiovascular Risk. / Maganty, Avinash; Osterberg, E. Charles; Ramasamy, Ranjith.

In: American Journal of Men's Health, Vol. 9, No. 4, 19.07.2015, p. 340-344.

Research output: Contribution to journalArticle

Maganty, Avinash ; Osterberg, E. Charles ; Ramasamy, Ranjith. / Hypogonadism and Testosterone Therapy : Associations With Cardiovascular Risk. In: American Journal of Men's Health. 2015 ; Vol. 9, No. 4. pp. 340-344.
@article{10bbef82f6084a9498584eafc0bc1f42,
title = "Hypogonadism and Testosterone Therapy: Associations With Cardiovascular Risk",
abstract = "Testosterone replacement therapy (TRT) use is increasing, primarily in men with symptomatic hypogonadism. There are many benefits associated with TRT use, including improved sexual function, improved bone mineral density, and increased free fat mass and strength. As TRT use increases, its role on cardiovascular health must be explored. While previous evidence identified no adverse cardiovascular risks associated with TRT use, more recent studies suggest that there may be an associated risk, especially in elderly men and younger men with cardiac disease. Care must be taken with TRT use in these groups of men by careful monitoring for cardiac dysfunction. While testosterone therapy has many benefits and may generally be well tolerated, those prescribing the therapy must be cognizant of the potential adverse cardiovascular risks and advise men on the potential risks versus benefits.",
keywords = "cardiovascular risk, testosterone replacement therapy (TRT)",
author = "Avinash Maganty and Osterberg, {E. Charles} and Ranjith Ramasamy",
year = "2015",
month = "7",
day = "19",
doi = "10.1177/1557988314540933",
language = "English (US)",
volume = "9",
pages = "340--344",
journal = "American Journal of Men's Health",
issn = "1557-9883",
publisher = "SAGE Publications Inc.",
number = "4",

}

TY - JOUR

T1 - Hypogonadism and Testosterone Therapy

T2 - Associations With Cardiovascular Risk

AU - Maganty, Avinash

AU - Osterberg, E. Charles

AU - Ramasamy, Ranjith

PY - 2015/7/19

Y1 - 2015/7/19

N2 - Testosterone replacement therapy (TRT) use is increasing, primarily in men with symptomatic hypogonadism. There are many benefits associated with TRT use, including improved sexual function, improved bone mineral density, and increased free fat mass and strength. As TRT use increases, its role on cardiovascular health must be explored. While previous evidence identified no adverse cardiovascular risks associated with TRT use, more recent studies suggest that there may be an associated risk, especially in elderly men and younger men with cardiac disease. Care must be taken with TRT use in these groups of men by careful monitoring for cardiac dysfunction. While testosterone therapy has many benefits and may generally be well tolerated, those prescribing the therapy must be cognizant of the potential adverse cardiovascular risks and advise men on the potential risks versus benefits.

AB - Testosterone replacement therapy (TRT) use is increasing, primarily in men with symptomatic hypogonadism. There are many benefits associated with TRT use, including improved sexual function, improved bone mineral density, and increased free fat mass and strength. As TRT use increases, its role on cardiovascular health must be explored. While previous evidence identified no adverse cardiovascular risks associated with TRT use, more recent studies suggest that there may be an associated risk, especially in elderly men and younger men with cardiac disease. Care must be taken with TRT use in these groups of men by careful monitoring for cardiac dysfunction. While testosterone therapy has many benefits and may generally be well tolerated, those prescribing the therapy must be cognizant of the potential adverse cardiovascular risks and advise men on the potential risks versus benefits.

KW - cardiovascular risk

KW - testosterone replacement therapy (TRT)

UR - http://www.scopus.com/inward/record.url?scp=84931446823&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84931446823&partnerID=8YFLogxK

U2 - 10.1177/1557988314540933

DO - 10.1177/1557988314540933

M3 - Article

C2 - 24972716

AN - SCOPUS:84931446823

VL - 9

SP - 340

EP - 344

JO - American Journal of Men's Health

JF - American Journal of Men's Health

SN - 1557-9883

IS - 4

ER -