The authors looked for mitral-valve prolapse in 40 patients with hyperthyroidism, either previously treated or active at the time of study. Forty-three per cent of these patients had mitral-valve prolapse on the basis of cardiac ausculation and echocardiography. This figure was significantly higher than the 18 per cent prevalence in a control group matched for age, sex, and race. The prevalence of mitral-valve prolapse did not differ between those who had a history of hyperthyroidism and those who were currently hyperparathyroid. Palpitations, tachycardia, and other cardiac arrhythmias, with nervousness and anxiety, may be manifestations of mitral-valve prolapse as well as of hyperthyroidism. Mistakenly attributing these symptoms to the activity of the thyroid disease rather than to mitral-valve prolapse may lead to unnecessary testing for hyperthyroidism and possibly to inappropriate treatment. Since prophylactic antibiotic treatment is recommended for patients with mitral-valve prolapse at the time of dental or surgical procedures, physicians should look carefully for this cardiac abnormality in patients with a history of hyperthyroidism.
|Number of pages||4|
|Journal||New England Journal of Medicine|
|State||Published - Dec 1 1981|
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