Hyperlipidaemia in renal transplant patients

Ronald B Goldberg, J. J. Judelman, A. Mindel, A. M. Meyers, D. J. Salant, J. A. Myburgh, R. Rabkin, B. I. Joffe, H. C. Seftel

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

The prevalence nature and possible aetiology of post transplantation hyperlipidaemia were studied in 94 renal allograft recipients. Sixty five per cent of the group had hypercholesterolaemia or hypertriglyceridaemia, and types IIb and IV were the commonest forms of hyperlipoproteinaemia encountered. The pathogenesis of post transplantation hyperlipidaemia is complex. Hypertriglyceridaemia was maximal in the first year after transplantation and could be correlated with high corticosteroid dosage during this period. Thereafter hypertriglyceridaemia was less marked and was related to obesity, carbohydrate intolerance and basal insulin levels. Mean cholesterol levels were elevated throughout the post transplantation period, varied little and could not be related to corticosteroid dosage, body weight, carbohydrate intolerance, basal insulin levels or renal dysfunction.

Original languageEnglish
Pages (from-to)1291-1294
Number of pages4
JournalSouth African Medical Journal
Volume50
Issue number33
StatePublished - Dec 1 1976
Externally publishedYes

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Hyperlipidemias
Hypertriglyceridemia
Transplantation
Transplants
Kidney
Adrenal Cortex Hormones
Insulin
Hyperlipoproteinemias
Hypercholesterolemia
Allografts
Obesity
Cholesterol
Body Weight
Glucose-Galactose Malabsorption

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Goldberg, R. B., Judelman, J. J., Mindel, A., Meyers, A. M., Salant, D. J., Myburgh, J. A., ... Seftel, H. C. (1976). Hyperlipidaemia in renal transplant patients. South African Medical Journal, 50(33), 1291-1294.

Hyperlipidaemia in renal transplant patients. / Goldberg, Ronald B; Judelman, J. J.; Mindel, A.; Meyers, A. M.; Salant, D. J.; Myburgh, J. A.; Rabkin, R.; Joffe, B. I.; Seftel, H. C.

In: South African Medical Journal, Vol. 50, No. 33, 01.12.1976, p. 1291-1294.

Research output: Contribution to journalArticle

Goldberg, RB, Judelman, JJ, Mindel, A, Meyers, AM, Salant, DJ, Myburgh, JA, Rabkin, R, Joffe, BI & Seftel, HC 1976, 'Hyperlipidaemia in renal transplant patients', South African Medical Journal, vol. 50, no. 33, pp. 1291-1294.
Goldberg RB, Judelman JJ, Mindel A, Meyers AM, Salant DJ, Myburgh JA et al. Hyperlipidaemia in renal transplant patients. South African Medical Journal. 1976 Dec 1;50(33):1291-1294.
Goldberg, Ronald B ; Judelman, J. J. ; Mindel, A. ; Meyers, A. M. ; Salant, D. J. ; Myburgh, J. A. ; Rabkin, R. ; Joffe, B. I. ; Seftel, H. C. / Hyperlipidaemia in renal transplant patients. In: South African Medical Journal. 1976 ; Vol. 50, No. 33. pp. 1291-1294.
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