Hyperlipidaemia in renal transplant patients

R. B. Goldberg; J. J. Judelman; A. Mindel; A. M. Meyers; D. J. Salant; J. A. Myburgh; R. Rabkin; B. I. Joffe; H. C. Seftel

Hyperlipidaemia in renal transplant patients

R. B. Goldberg, J. J. Judelman, A. Mindel, A. M. Meyers, D. J. Salant, J. A. Myburgh, R. Rabkin, B. I. Joffe, H. C. Seftel

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

Abstract

The prevalence nature and possible aetiology of post transplantation hyperlipidaemia were studied in 94 renal allograft recipients. Sixty five per cent of the group had hypercholesterolaemia or hypertriglyceridaemia, and types IIb and IV were the commonest forms of hyperlipoproteinaemia encountered. The pathogenesis of post transplantation hyperlipidaemia is complex. Hypertriglyceridaemia was maximal in the first year after transplantation and could be correlated with high corticosteroid dosage during this period. Thereafter hypertriglyceridaemia was less marked and was related to obesity, carbohydrate intolerance and basal insulin levels. Mean cholesterol levels were elevated throughout the post transplantation period, varied little and could not be related to corticosteroid dosage, body weight, carbohydrate intolerance, basal insulin levels or renal dysfunction.

Original language	English (US)
Pages (from-to)	1291-1294
Number of pages	4
Journal	South African Medical Journal
Volume	50
Issue number	33
State	Published - Dec 1 1976
Externally published	Yes

ASJC Scopus subject areas

Medicine(all)

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This output contributes to the following Sustainable Development Goal(s)

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title = "Hyperlipidaemia in renal transplant patients",

abstract = "The prevalence nature and possible aetiology of post transplantation hyperlipidaemia were studied in 94 renal allograft recipients. Sixty five per cent of the group had hypercholesterolaemia or hypertriglyceridaemia, and types IIb and IV were the commonest forms of hyperlipoproteinaemia encountered. The pathogenesis of post transplantation hyperlipidaemia is complex. Hypertriglyceridaemia was maximal in the first year after transplantation and could be correlated with high corticosteroid dosage during this period. Thereafter hypertriglyceridaemia was less marked and was related to obesity, carbohydrate intolerance and basal insulin levels. Mean cholesterol levels were elevated throughout the post transplantation period, varied little and could not be related to corticosteroid dosage, body weight, carbohydrate intolerance, basal insulin levels or renal dysfunction.",

author = "Goldberg, {R. B.} and Judelman, {J. J.} and A. Mindel and Meyers, {A. M.} and Salant, {D. J.} and Myburgh, {J. A.} and R. Rabkin and Joffe, {B. I.} and Seftel, {H. C.}",

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T1 - Hyperlipidaemia in renal transplant patients

AU - Goldberg, R. B.

AU - Judelman, J. J.

AU - Mindel, A.

AU - Meyers, A. M.

AU - Salant, D. J.

AU - Myburgh, J. A.

AU - Rabkin, R.

AU - Joffe, B. I.

AU - Seftel, H. C.

PY - 1976/12/1

Y1 - 1976/12/1

N2 - The prevalence nature and possible aetiology of post transplantation hyperlipidaemia were studied in 94 renal allograft recipients. Sixty five per cent of the group had hypercholesterolaemia or hypertriglyceridaemia, and types IIb and IV were the commonest forms of hyperlipoproteinaemia encountered. The pathogenesis of post transplantation hyperlipidaemia is complex. Hypertriglyceridaemia was maximal in the first year after transplantation and could be correlated with high corticosteroid dosage during this period. Thereafter hypertriglyceridaemia was less marked and was related to obesity, carbohydrate intolerance and basal insulin levels. Mean cholesterol levels were elevated throughout the post transplantation period, varied little and could not be related to corticosteroid dosage, body weight, carbohydrate intolerance, basal insulin levels or renal dysfunction.

AB - The prevalence nature and possible aetiology of post transplantation hyperlipidaemia were studied in 94 renal allograft recipients. Sixty five per cent of the group had hypercholesterolaemia or hypertriglyceridaemia, and types IIb and IV were the commonest forms of hyperlipoproteinaemia encountered. The pathogenesis of post transplantation hyperlipidaemia is complex. Hypertriglyceridaemia was maximal in the first year after transplantation and could be correlated with high corticosteroid dosage during this period. Thereafter hypertriglyceridaemia was less marked and was related to obesity, carbohydrate intolerance and basal insulin levels. Mean cholesterol levels were elevated throughout the post transplantation period, varied little and could not be related to corticosteroid dosage, body weight, carbohydrate intolerance, basal insulin levels or renal dysfunction.

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Hyperlipidaemia in renal transplant patients

Abstract

ASJC Scopus subject areas

UN SDGs

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