Hyperlipidaemia in renal transplant patients

R. B. Goldberg, J. J. Judelman, A. Mindel, A. M. Meyers, D. J. Salant, J. A. Myburgh, R. Rabkin, B. I. Joffe, H. C. Seftel

Research output: Contribution to journalArticle

9 Scopus citations

Abstract

The prevalence nature and possible aetiology of post transplantation hyperlipidaemia were studied in 94 renal allograft recipients. Sixty five per cent of the group had hypercholesterolaemia or hypertriglyceridaemia, and types IIb and IV were the commonest forms of hyperlipoproteinaemia encountered. The pathogenesis of post transplantation hyperlipidaemia is complex. Hypertriglyceridaemia was maximal in the first year after transplantation and could be correlated with high corticosteroid dosage during this period. Thereafter hypertriglyceridaemia was less marked and was related to obesity, carbohydrate intolerance and basal insulin levels. Mean cholesterol levels were elevated throughout the post transplantation period, varied little and could not be related to corticosteroid dosage, body weight, carbohydrate intolerance, basal insulin levels or renal dysfunction.

Original languageEnglish (US)
Pages (from-to)1291-1294
Number of pages4
JournalSouth African Medical Journal
Volume50
Issue number33
StatePublished - Dec 1 1976
Externally publishedYes

ASJC Scopus subject areas

  • Medicine(all)

Fingerprint Dive into the research topics of 'Hyperlipidaemia in renal transplant patients'. Together they form a unique fingerprint.

  • Cite this

    Goldberg, R. B., Judelman, J. J., Mindel, A., Meyers, A. M., Salant, D. J., Myburgh, J. A., Rabkin, R., Joffe, B. I., & Seftel, H. C. (1976). Hyperlipidaemia in renal transplant patients. South African Medical Journal, 50(33), 1291-1294.