Hyperinfection strongyloidiasis in a liver transplant recipient treated with parenteral ivermectin: Case report

P. Lichtenberger, I. Rosa-Cunha, M. Morris, S. Nishida, E. Akpinar, J. Gaitan, A. Tzakis, Susanne Doblecki-Lewis

Research output: Contribution to journalArticle

27 Scopus citations

Abstract

Severe strongyloidiasis, including hyperinfection and dissemination, is a recognized complication of solid organ transplantation. However, the development of strongyloidiasis in a liver transplant recipient has not been previously described. We present a case of severe strongyloidiasis occurring in a patient 4 months after liver transplantation and 1 month after receiving treatment for acute rejection. We assess the management challenges in this patient who remained symptomatic despite oral treatment with ivermectin and albendazole and eventual successful treatment with parenteral ivermectin. We review the published experience with alternative methods of ivermectin administration. We also investigate the possible source of infection, as the patient was not from an endemic area.

Original languageEnglish (US)
Pages (from-to)137-142
Number of pages6
JournalTransplant Infectious Disease
Volume11
Issue number2
DOIs
StatePublished - Apr 1 2009

Keywords

  • Liver transplantation
  • Parenteral ivermectin
  • Severe strongyloidiasis
  • Strongyloides stercoralis

ASJC Scopus subject areas

  • Transplantation
  • Infectious Diseases

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