Hyperhidrosis and stress

Vincent M. Hsu, Vidhi V. Shah, Adam S. Aldahan, Stephanie Mlacker, Sahal Samarkandy, Keyvan Nouri

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations


Hyperhidrosis is a psychological skin condition characterized by uncontrollable, excessive amounts of sweat in specific body locations. Although not a physically debilitating condition, those individuals affected with this condition commonly experience psychosocial stress during regular social encounters and exhibit low self-confidence, thus drastically decreasing the quality of life of these individuals (Coutinho dos Santos et al. Pediatr Dermatol 26(4):439-444, 2009; Glogau, Dermatol Surg 24(8):817-819, 1998; Kouris et al. Pediatr Dermatol 32(2):226-230, 2015). Hyperhidrosis is often diagnosed in patients suffering from psychosocial disorders such as social anxiety, suggesting a psychological factor may influence it’s onset. Various management options exist for the treatment of hyperhidrosis including fractionated microneedle radio (FMR) treatment, botulinum toxin type A (BTXA), surgery, oral administration of the anticholinergic drug glycopyrronium bromide (glycopyrrolate), aluminum chloride antiperspirants, iontophoresis, and endoscopic thoracic sympathectomy (Glogau, Dermatol Surg 24(8):817-819, 1998; Kouris et al. Pediatr Dermatol 32(2):226-230, 2015; Bajaj and Langtry, Br J Dermatol 157(1):118-121, 2007; Fatemi Naeini et al. Australas J Dermatol 56(4):279-284, 2015; Kobayashi et al. J Dermatol 21(8):575-581, 1994; Rompel and Scholz, J Eur Acad Dermatol Venereol 15(3):207-211, 2001). Currently, endoscopic thoracic sympathectomy is the only current, permanent treatment option. However, new therapeutic options on the horizon such as lasers and microwave thermolysis demonstrate promising results.

Original languageEnglish (US)
Title of host publicationStress and Skin Disorders
Subtitle of host publicationBasic and Clinical Aspects
PublisherSpringer International Publishing
Number of pages12
ISBN (Electronic)9783319463520
ISBN (Print)9783319463513
StatePublished - Jan 1 2016


  • Anxiety
  • Hyperhidrosis
  • Psychological
  • Skin
  • Stress
  • Sweat
  • Treatment

ASJC Scopus subject areas

  • Medicine(all)


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