Hyperglycemia and plasmid lipid levels: Covariations in insulin-dependent diabetes

Jay M Sosenko, J. Breslow, O. S. Miettinen, K. H. Gabbay

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

Longitudinal relationships of plasma lipids with parameters of blood glucose control were studied in 124 young insulin-dependent diabetic patients who had multiple, simultaneous determinations of these parameters during a 1-yr period. Fluctuations in hemoglobin A1, a cumulative measure of blood glucose control, correlated with fluctuations in total cholesterol (r = 0.19, P < 0.001) and low-density lipoprotein-cholesterol (r = 0.17, P < 0.001). Similarly, fluctuations in fasting blood glucose correlated with those in total cholesterol (r = 0.20, P < 0.001), very low-density lipoprotein-cholesterol (r = 0.13, P = 0.002), and total triglyceride (r = 0.23, P < 0.001). These data indicate covariation between plasma lipid and blood glucose control parameters and suggest that poor blood glucose control contributes to the excess risk of coronary heart disease in insulin-dependent diabetes mellitus.

Original languageEnglish
Pages (from-to)40-43
Number of pages4
JournalDiabetes Care
Volume5
Issue number1
StatePublished - Jan 1 1982
Externally publishedYes

Fingerprint

Hyperglycemia
Blood Glucose
Plasmids
Insulin
Lipids
Cholesterol
VLDL Cholesterol
Type 1 Diabetes Mellitus
LDL Cholesterol
Coronary Disease
Fasting
Hemoglobins
Triglycerides

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Internal Medicine

Cite this

Sosenko, J. M., Breslow, J., Miettinen, O. S., & Gabbay, K. H. (1982). Hyperglycemia and plasmid lipid levels: Covariations in insulin-dependent diabetes. Diabetes Care, 5(1), 40-43.

Hyperglycemia and plasmid lipid levels : Covariations in insulin-dependent diabetes. / Sosenko, Jay M; Breslow, J.; Miettinen, O. S.; Gabbay, K. H.

In: Diabetes Care, Vol. 5, No. 1, 01.01.1982, p. 40-43.

Research output: Contribution to journalArticle

Sosenko, JM, Breslow, J, Miettinen, OS & Gabbay, KH 1982, 'Hyperglycemia and plasmid lipid levels: Covariations in insulin-dependent diabetes', Diabetes Care, vol. 5, no. 1, pp. 40-43.
Sosenko, Jay M ; Breslow, J. ; Miettinen, O. S. ; Gabbay, K. H. / Hyperglycemia and plasmid lipid levels : Covariations in insulin-dependent diabetes. In: Diabetes Care. 1982 ; Vol. 5, No. 1. pp. 40-43.
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