Hypercortisolemia and dysregulation of the hypothalamic-pituitary-adrenal (HPA) axis are often found in severe forms of depression. The authors review the history of techniques used to assess the functions of the HPA axis, evidence for hypercortisolemia as a state rather than trait component of depression, and treatment implications.
|Original language||English (US)|
|Issue number||SUPPL. 1|
|State||Published - Jan 1 2005|
- Corticotropin-releasing factor
ASJC Scopus subject areas
- Psychiatry and Mental health