Hypercortisolemia and depression

Charles F. Gillespie, Charles B. Nemeroff

Research output: Contribution to journalReview article

235 Scopus citations

Abstract

Hypercortisolemia and dysregulation of the hypothalamic-pituitary-adrenal (HPA) axis are often found in severe forms of depression. The authors review the history of techniques used to assess the functions of the HPA axis, evidence for hypercortisolemia as a state rather than trait component of depression, and treatment implications.

Original languageEnglish (US)
Pages (from-to)S26-S28
JournalPsychosomatic medicine
Volume67
Issue numberSUPPL. 1
DOIs
StatePublished - Jan 1 2005
Externally publishedYes

Keywords

  • Corticotropin-releasing factor
  • Cortisol
  • Depression
  • Dexamethasone
  • Hypercortisolemia

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Psychology(all)

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