Hypercoagulability and venous thromboembolism in burn patients

Jonathan P. Meizoso, Juliet J. Ray, Casey J. Allen, Robert M. Van Haren, Gabriel Ruiz, Nicholas Namias, Carl I. Schulman, Louis R. Pizano, Kenneth G. Proctor

Research output: Contribution to journalArticle

17 Scopus citations

Abstract

To our knowledge, this is the first comprehensive review on the subject of venous thromboembolism (VTE) and hypercoagulability in burn patients. Specific changes in coagulability are reviewed using data from thromboelastography and other techniques. Disseminated intravascular coagulation in burn patients is discussed. The incidence and risk factors associated with VTE in burn patients are then examined, followed by the use of low-molecular-weight heparin thromboprophylaxis and monitoring techniques using antifactor Xa levels. The need for large, prospective trials in burn patients is highlighted, especially in the areas of VTE incidence and safe, effective thromboprophylaxis.

Original languageEnglish (US)
Pages (from-to)43-48
Number of pages6
JournalSeminars in Thrombosis and Hemostasis
Volume41
Issue number1
DOIs
StatePublished - Feb 1 2015

Keywords

  • burns
  • enoxaparin
  • hypercoagulability
  • thrombosis
  • venous thromboembolism

ASJC Scopus subject areas

  • Hematology
  • Cardiology and Cardiovascular Medicine

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