Hypercalcemia in epidermoid carcinoma of the head and neck

W. Jarrard Goodwin, J. Ryan Chandler

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

Hypercalcemia occurs rarely at the time of diagnosis in patients found to have epidermoid carcinoma of the head and neck. It is particularly unlikely in those patients who present with potentially curable lesions. Only 2 of our 307 patients who presented with potentially curable lesions were hypercalcemic at the time of diagnosis. Two hundred thirty-eight of these patients were followed up for two years or until death. Of the 139 who did not remain free of disease, hypercalcemia of clinical significance developed in ten (7.2 per cent). Pseudohyperparathyroidism was the suspected cause in seven of twelve patients. Debilitating symptoms were present in all patients with serum calcium levels greater than 12.0 mg/100 ml. Treatment, when given, was effective in alleviating gastrointestinal and central nervous system problems. Although usually temporary, symptomatic improvement was appreciated by most patients and family members.

Original languageEnglish
Pages (from-to)444-448
Number of pages5
JournalThe American Journal of Surgery
Volume132
Issue number4
DOIs
StatePublished - Jan 1 1976
Externally publishedYes

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Hypercalcemia
Squamous Cell Carcinoma
Neck
Head
Central Nervous System
Calcium
Serum

ASJC Scopus subject areas

  • Surgery

Cite this

Hypercalcemia in epidermoid carcinoma of the head and neck. / Goodwin, W. Jarrard; Chandler, J. Ryan.

In: The American Journal of Surgery, Vol. 132, No. 4, 01.01.1976, p. 444-448.

Research output: Contribution to journalArticle

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