Hyaline membrane disease. Comparison of continuous negative pressure and nasal positive airway pressure in its treatment

G. Alexander, T. Gerhardt, Eduardo Bancalari

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

The effectiveness of continuous negative pressure (CNP) and nasal continuous positive airway pressure (CPAP) in the treatment of hyaline membrane disease and the incidence of complications were compared in 36 preterm infants randomly treated with CNP or nasal CPAP. Both methods of treatment were effective in increasing PaO2 and allowing a decrease in inspired O2 concentration. The time required with mechanical assistance and with an O2 concentration of more than 40% was equal in both groups. In the CNP group, four infants required mechanical ventilation because of clinical deterioration whereas in the nasal CPAP group, seven needed this type of therapy. Three infants in each group had extraalveolar air, and two patients in each group died. The results suggest that both methods of applying continuous distending airway pressure are effective. Nasal CPAP has the advantages of easier application and better access to the infant.

Original languageEnglish
Pages (from-to)1156-1159
Number of pages4
JournalAmerican Journal of Diseases of Children
Volume133
Issue number11
StatePublished - Dec 1 1979

Fingerprint

Hyaline Membrane Disease
Continuous Positive Airway Pressure
Pressure
Therapeutics
Artificial Respiration
Premature Infants
Air
Incidence

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

Cite this

Hyaline membrane disease. Comparison of continuous negative pressure and nasal positive airway pressure in its treatment. / Alexander, G.; Gerhardt, T.; Bancalari, Eduardo.

In: American Journal of Diseases of Children, Vol. 133, No. 11, 01.12.1979, p. 1156-1159.

Research output: Contribution to journalArticle

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