Huntington disease in Maryland

Clinical aspects of racial variation

S. E. Folstein, G. A. Chase, W. E. Wahl, A. M. McDonnell, M. F. Folstein

Research output: Contribution to journalArticle

113 Citations (Scopus)

Abstract

In a Maryland survey of Huntington disease, the prevalence in blacks was unexpectedly high and equal to that in whites. Age at onset was earlier in blacks, and their clinical features, at all ages at onset, were similar to those seen in juvenile-onset Huntington disease. Blacks had more severe bradykinesia and abnormalities of eye movement and less frequent psychiatric disorder, particularly depression.

Original languageEnglish
Pages (from-to)168-179
Number of pages12
JournalAmerican Journal of Human Genetics
Volume41
Issue number2
StatePublished - Jan 1 1987

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Huntington Disease
Age of Onset
Hypokinesia
Eye Movements
Psychiatry
Depression

ASJC Scopus subject areas

  • Genetics

Cite this

Folstein, S. E., Chase, G. A., Wahl, W. E., McDonnell, A. M., & Folstein, M. F. (1987). Huntington disease in Maryland: Clinical aspects of racial variation. American Journal of Human Genetics, 41(2), 168-179.

Huntington disease in Maryland : Clinical aspects of racial variation. / Folstein, S. E.; Chase, G. A.; Wahl, W. E.; McDonnell, A. M.; Folstein, M. F.

In: American Journal of Human Genetics, Vol. 41, No. 2, 01.01.1987, p. 168-179.

Research output: Contribution to journalArticle

Folstein, SE, Chase, GA, Wahl, WE, McDonnell, AM & Folstein, MF 1987, 'Huntington disease in Maryland: Clinical aspects of racial variation', American Journal of Human Genetics, vol. 41, no. 2, pp. 168-179.
Folstein SE, Chase GA, Wahl WE, McDonnell AM, Folstein MF. Huntington disease in Maryland: Clinical aspects of racial variation. American Journal of Human Genetics. 1987 Jan 1;41(2):168-179.
Folstein, S. E. ; Chase, G. A. ; Wahl, W. E. ; McDonnell, A. M. ; Folstein, M. F. / Huntington disease in Maryland : Clinical aspects of racial variation. In: American Journal of Human Genetics. 1987 ; Vol. 41, No. 2. pp. 168-179.
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