Human peripheral blood and splenic T lymphocyte reactions versus kidney cortical cells

David Roth, G. K. Kyriakides, L. Fuller, J. Miller

Research output: Contribution to journalArticle

Abstract

These data suggest that a lymphoproliferative response to kidney-specific antigens might have been unmasked or amplified by the enzymatic digestion (collagenase, neuraminidase) used in deriving the KC cell population, a reaction not dependent on Ia antigens (at least as defined by L243 anti-DR antibody) as in the allogeneic response. The MLKC data obtained using infiltrating lymphocytes isolated from ESRD kidneys provokes questions regarding the contribution of T cell-mediated autoimmunity in the progression to chronic renal failure.

Original languageEnglish
Pages (from-to)1532-1534
Number of pages3
JournalTransplantation Proceedings
Volume16
Issue number6
StatePublished - Dec 1 1984

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Chronic Kidney Failure
T-Lymphocytes
Kidney
Histocompatibility Antigens Class II
Neuraminidase
Collagenases
Autoimmunity
Digestion
Anti-Idiotypic Antibodies
Lymphocytes
Antigens
Population

ASJC Scopus subject areas

  • Surgery
  • Transplantation

Cite this

Human peripheral blood and splenic T lymphocyte reactions versus kidney cortical cells. / Roth, David; Kyriakides, G. K.; Fuller, L.; Miller, J.

In: Transplantation Proceedings, Vol. 16, No. 6, 01.12.1984, p. 1532-1534.

Research output: Contribution to journalArticle

Roth, D, Kyriakides, GK, Fuller, L & Miller, J 1984, 'Human peripheral blood and splenic T lymphocyte reactions versus kidney cortical cells', Transplantation Proceedings, vol. 16, no. 6, pp. 1532-1534.
Roth, David ; Kyriakides, G. K. ; Fuller, L. ; Miller, J. / Human peripheral blood and splenic T lymphocyte reactions versus kidney cortical cells. In: Transplantation Proceedings. 1984 ; Vol. 16, No. 6. pp. 1532-1534.
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