Human ocular biometry

Robert C. Augusteyn, Derek Nankivil, Ashik Mohamed, Bianca Maceo, Faradia Pierre, Jean-Marie A Parel

Research output: Contribution to journalArticle

36 Citations (Scopus)

Abstract

The aim of this study was to examine growth of the human eye globe and cornea from early in gestation to late in adult life. Globe antero-posterior length, horizontal and vertical diameters, corneal horizontal and vertical (white to white) diameters and posterior pole to limbus distances were measured using digital calipers (±0.01 mm) in 541 postmortem eyes. Additional pre- and postnatal data for some of the dimensions were obtained from the literature. All dimensions examined increase rapidly during prenatal development but postnatal growth differs. Growth of globe antero-posterior length, vertical and horizontal diameters as well as corneal vertical and horizontal diameters stops within 1 year after birth. Logistic analysis is consistent with an asymptotic prenatal growth mode and no further growth after its completion around 1 year after birth. Horizontal and vertical globe diameters are the same at all ages but the corneal horizontal diameter is always larger than the vertical diameter. No differences could be detected between males and females in any of the ocular dimensions. Globe and corneal growth take place primarily during the prenatal growth mode and dimensions reach their maxima, shortly after birth. It is suggested that cessation of a growth stimulating signal at birth marks the end of the prenatal growth mode and that the small increases over the next year are due to cells already stimulated. Male and female eyes of the same age have the same globe and cornea dimensions.

Original languageEnglish
Pages (from-to)70-75
Number of pages6
JournalExperimental Eye Research
Volume102
DOIs
StatePublished - Sep 1 2012

Fingerprint

Biometry
Growth
Parturition
Cornea
Growth and Development
Pregnancy

Keywords

  • Corneal dimensions
  • Gender
  • Globe dimensions
  • Human
  • Ocular growth

ASJC Scopus subject areas

  • Ophthalmology
  • Sensory Systems
  • Cellular and Molecular Neuroscience

Cite this

Augusteyn, R. C., Nankivil, D., Mohamed, A., Maceo, B., Pierre, F., & Parel, J-M. A. (2012). Human ocular biometry. Experimental Eye Research, 102, 70-75. https://doi.org/10.1016/j.exer.2012.06.009

Human ocular biometry. / Augusteyn, Robert C.; Nankivil, Derek; Mohamed, Ashik; Maceo, Bianca; Pierre, Faradia; Parel, Jean-Marie A.

In: Experimental Eye Research, Vol. 102, 01.09.2012, p. 70-75.

Research output: Contribution to journalArticle

Augusteyn, RC, Nankivil, D, Mohamed, A, Maceo, B, Pierre, F & Parel, J-MA 2012, 'Human ocular biometry', Experimental Eye Research, vol. 102, pp. 70-75. https://doi.org/10.1016/j.exer.2012.06.009
Augusteyn RC, Nankivil D, Mohamed A, Maceo B, Pierre F, Parel J-MA. Human ocular biometry. Experimental Eye Research. 2012 Sep 1;102:70-75. https://doi.org/10.1016/j.exer.2012.06.009
Augusteyn, Robert C. ; Nankivil, Derek ; Mohamed, Ashik ; Maceo, Bianca ; Pierre, Faradia ; Parel, Jean-Marie A. / Human ocular biometry. In: Experimental Eye Research. 2012 ; Vol. 102. pp. 70-75.
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