Human immunodeficiency virus cultured from bone. Implications for transplantation

B. E. Buck, L. Resnick, S. M. Shah, Theodore Malinin

Research output: Contribution to journalArticle

219 Citations (Scopus)

Abstract

This study demonstrates by a virologic culture method that human immunodeficiency virus (HIV) resides in bone. After freezing, some initially positive specimens no longer yielded virus, but those that continued to yield virus were not further altered by subsequent washing, which removed essentially all marrow, or by freeze-drying. The safeguards against potential transmission of HIV by a bone allograft are principally the screening and testing methods previously described, although there may be a further reduction of the remote residual risk by the freezing step in the usual technical sequence for tissue banking by sterile techniques.

Original languageEnglish
Pages (from-to)249-253
Number of pages5
JournalClinical Orthopaedics and Related Research
Issue number251
StatePublished - Jan 1 1990

Fingerprint

Freezing
Transplantation
HIV
Tissue Banks
Viruses
Bone and Bones
Freeze Drying
Allografts
Bone Marrow

ASJC Scopus subject areas

  • Orthopedics and Sports Medicine
  • Surgery

Cite this

Human immunodeficiency virus cultured from bone. Implications for transplantation. / Buck, B. E.; Resnick, L.; Shah, S. M.; Malinin, Theodore.

In: Clinical Orthopaedics and Related Research, No. 251, 01.01.1990, p. 249-253.

Research output: Contribution to journalArticle

Buck, B. E. ; Resnick, L. ; Shah, S. M. ; Malinin, Theodore. / Human immunodeficiency virus cultured from bone. Implications for transplantation. In: Clinical Orthopaedics and Related Research. 1990 ; No. 251. pp. 249-253.
@article{50818dabc2c9493094c9a6da8ce08353,
title = "Human immunodeficiency virus cultured from bone. Implications for transplantation",
abstract = "This study demonstrates by a virologic culture method that human immunodeficiency virus (HIV) resides in bone. After freezing, some initially positive specimens no longer yielded virus, but those that continued to yield virus were not further altered by subsequent washing, which removed essentially all marrow, or by freeze-drying. The safeguards against potential transmission of HIV by a bone allograft are principally the screening and testing methods previously described, although there may be a further reduction of the remote residual risk by the freezing step in the usual technical sequence for tissue banking by sterile techniques.",
author = "Buck, {B. E.} and L. Resnick and Shah, {S. M.} and Theodore Malinin",
year = "1990",
month = "1",
day = "1",
language = "English",
pages = "249--253",
journal = "Clinical Orthopaedics and Related Research",
issn = "0009-921X",
publisher = "Springer New York",
number = "251",

}

TY - JOUR

T1 - Human immunodeficiency virus cultured from bone. Implications for transplantation

AU - Buck, B. E.

AU - Resnick, L.

AU - Shah, S. M.

AU - Malinin, Theodore

PY - 1990/1/1

Y1 - 1990/1/1

N2 - This study demonstrates by a virologic culture method that human immunodeficiency virus (HIV) resides in bone. After freezing, some initially positive specimens no longer yielded virus, but those that continued to yield virus were not further altered by subsequent washing, which removed essentially all marrow, or by freeze-drying. The safeguards against potential transmission of HIV by a bone allograft are principally the screening and testing methods previously described, although there may be a further reduction of the remote residual risk by the freezing step in the usual technical sequence for tissue banking by sterile techniques.

AB - This study demonstrates by a virologic culture method that human immunodeficiency virus (HIV) resides in bone. After freezing, some initially positive specimens no longer yielded virus, but those that continued to yield virus were not further altered by subsequent washing, which removed essentially all marrow, or by freeze-drying. The safeguards against potential transmission of HIV by a bone allograft are principally the screening and testing methods previously described, although there may be a further reduction of the remote residual risk by the freezing step in the usual technical sequence for tissue banking by sterile techniques.

UR - http://www.scopus.com/inward/record.url?scp=0025321185&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0025321185&partnerID=8YFLogxK

M3 - Article

C2 - 2295182

AN - SCOPUS:0025321185

SP - 249

EP - 253

JO - Clinical Orthopaedics and Related Research

JF - Clinical Orthopaedics and Related Research

SN - 0009-921X

IS - 251

ER -