Abstract
During in vitro fertilization, embryos deemed clinically useless based on poor morphology are typically discarded. Here we demonstrate a statistical correlation between the developmental stage of such poor-quality embryos and the yield of human embryonic stem (hES) cell lines. Early-arrested or highly fragmented embryos only rarely yield cell lines, whereas those that have achieved blastocyst stage are a robust source of normal hES cells.
Original language | English (US) |
---|---|
Pages (from-to) | 212-214 |
Number of pages | 3 |
Journal | Nature Biotechnology |
Volume | 26 |
Issue number | 2 |
DOIs | |
State | Published - Feb 2008 |
Externally published | Yes |
ASJC Scopus subject areas
- Biotechnology
- Bioengineering
- Applied Microbiology and Biotechnology
- Molecular Medicine
- Biomedical Engineering