Human bone and tissue allografts: Preparation and safety

B. E. Buck, T. I. Malinin

Research output: Contribution to journalArticlepeer-review

121 Scopus citations


Currently, modern tissue banks routinely supply requested bone and soft- tissue allografts. These allografts are safe if tissue-bank personnel adhere to the existing methodology for excluding any donors with potential for disease transmission. The authors' discard rate after excision of tissues has been approximately 18%, reflecting their concern for allograft safety. The preparation of significant numbers of allografts is labor intensive and very expensive, as is multiphasic screening of donors. However, long-term success with a large number of bone or soft-tissue recipient patients has led physicians and patients to have confidence in the safety of allografts prepared as described.

Original languageEnglish (US)
Pages (from-to)8-17
Number of pages10
JournalClinical orthopaedics and related research
Issue number303
StatePublished - Jan 1 1994

ASJC Scopus subject areas

  • Surgery
  • Orthopedics and Sports Medicine


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