Abstract
Perforation of membranes and pore formation is mediated by polymerization of proteins of the immune system, complement C9 and Perforin, which share the conserved MACPF domain. In this issue of Immunity, Baran et al. (2009) identify the molecular mechanism initiating polymerization as charge interactions in the MACPF domain.
Original language | English (US) |
---|---|
Pages (from-to) | 668-670 |
Number of pages | 3 |
Journal | Immunity |
Volume | 30 |
Issue number | 5 |
DOIs | |
State | Published - May 22 2009 |
ASJC Scopus subject areas
- Immunology and Allergy
- Immunology
- Infectious Diseases