How to Polymerize in Order to Survive

Eckhard R. Podack

Research output: Contribution to journalShort survey

3 Scopus citations

Abstract

Perforation of membranes and pore formation is mediated by polymerization of proteins of the immune system, complement C9 and Perforin, which share the conserved MACPF domain. In this issue of Immunity, Baran et al. (2009) identify the molecular mechanism initiating polymerization as charge interactions in the MACPF domain.

Original languageEnglish (US)
Pages (from-to)668-670
Number of pages3
JournalImmunity
Volume30
Issue number5
DOIs
StatePublished - May 22 2009

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology
  • Infectious Diseases

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