How to Polymerize in Order to Survive

Eckhard R. Podack

doi:10.1016/j.immuni.2009.04.004

How to Polymerize in Order to Survive

Eckhard R. Podack

Microbiology & Immunology

Research output: Contribution to journal › Short survey › peer-review

3 Scopus citations

Abstract

Perforation of membranes and pore formation is mediated by polymerization of proteins of the immune system, complement C9 and Perforin, which share the conserved MACPF domain. In this issue of Immunity, Baran et al. (2009) identify the molecular mechanism initiating polymerization as charge interactions in the MACPF domain.

Original language	English (US)
Pages (from-to)	668-670
Number of pages	3
Journal	Immunity
Volume	30
Issue number	5
DOIs	https://doi.org/10.1016/j.immuni.2009.04.004
State	Published - May 22 2009

ASJC Scopus subject areas

Immunology and Allergy
Immunology
Infectious Diseases

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abstract = "Perforation of membranes and pore formation is mediated by polymerization of proteins of the immune system, complement C9 and Perforin, which share the conserved MACPF domain. In this issue of Immunity, Baran et al. (2009) identify the molecular mechanism initiating polymerization as charge interactions in the MACPF domain.",

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