Host mating system and the spread of a disease-resistant allele in a population

Donald L DeAngelis, Jennifer M. Koslow, Jiang Jiang, Shigui Ruan

Research output: Contribution to journalArticle

1 Scopus citations

Abstract

The model presented here modifies a susceptible-infected (SI) host-pathogen model to determine the influence of mating system on the outcome of a host-pathogen interaction. Both deterministic and stochastic (individual-based) versions of the model were used. This model considers the potential consequences of varying mating systems on the rate of spread of both the pathogen and resistance alleles within the population. We assumed that a single allele for disease resistance was sufficient to confer complete resistance in an individual, and that both homozygote and heterozygote resistant individuals had the same mean birth and death rates. When disease invaded a population with only an initial small fraction of resistant genes, inbreeding (selfing) tended to increase the probability that the disease would soon be eliminated from a small population rather than become endemic, while outcrossing greatly increased the probability that the population would become extinct due to the disease.

Original languageEnglish (US)
Pages (from-to)191-198
Number of pages8
JournalTheoretical Population Biology
Volume74
Issue number2
DOIs
StatePublished - Sep 1 2008

Keywords

  • Allele spread
  • Disease resistance
  • Inbreeding
  • Pathogen spread
  • Plant pathogens
  • Resistant alleles
  • Susceptible-infected-resistant model

ASJC Scopus subject areas

  • Agricultural and Biological Sciences(all)
  • Ecology, Evolution, Behavior and Systematics

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