Other data reveal the important prognostic value of estrogen-receptor determinations in identifying patients at greater risk of relapse. The data of Drs. Legha et al. do not allow any conclusions on the effect of receptor status, as assessed (indirectly) by previous hormone responsiveness on response to chemotherapy. Dr. Panko has identified important potential problems with the study of Kiang et al. There is no question that some estrogen-receptor tumors can on substquent biopsies be estrogen-receptor positive; chemotherapy may enhance this selection of cells.
|Original language||English (US)|
|Number of pages||1|
|Journal||New England Journal of Medicine|
|State||Published - May 3 1979|
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