HLA antigens and corticosteroid response

Bernard Becker, Dong H. Shin, Paul F. Palmberg, Stephen R. Waltman

Research output: Contribution to journalArticle

30 Scopus citations

Abstract

Compared with normal individuals, patients with primary open angle glaucoma have increased prevalences of HLA B12 and B7 antigens and are more responsive to glucocorticoids. Lymphocytes from both ocular normotensive and glaucomatous individuals with the HLA B12 antigen require significantly (P<.02) lower concentrations of prednisolone to inhibit phytohemagglutinin induced transformation.

Original languageEnglish (US)
Pages (from-to)1427-1428
Number of pages2
JournalScience
Volume194
Issue number4272
DOIs
StatePublished - Jan 1 1976
Externally publishedYes

ASJC Scopus subject areas

  • General

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    Becker, B., Shin, D. H., Palmberg, P. F., & Waltman, S. R. (1976). HLA antigens and corticosteroid response. Science, 194(4272), 1427-1428. https://doi.org/10.1126/science.1006308