HIV/AIDS patients with HIV vasculopathy and VZV vasculitis: A case series

J. Gutierrez, G. Ortiz

Research output: Contribution to journalArticlepeer-review

29 Scopus citations


Purpose Stroke is a rising cause of mortality in human immunodeficiency virus (HIV) and acquired immunodeficiency syndrome (AIDS) populations. The etiology of stroke remains at the core of the decision-making process to treat and prevent recurrent events. In this population HIV vasculopathy (HIV-V) and varicella zoster virus (VZV) vasculitis are elusive causes of stroke. This study investigated radiological markers that could help identify possible etiological causes. Methods A series of nine consecutive patients seen at a large metropolitan hospital who presented with AIDS and stroke with the suspicion of either HIV vasculopathy (HIVV) or VZV vasculitis (VZV-V) were included. A standardized diagnostic approach was used to for HIV-V and VZVV. Data on frequencies and typical images are reported. Results Of the nine patients five had VZV-V and four had HIV-V. Patients with VZV-V were generally younger than those with HIV-V; however, no other significant demographic or cardiovascular differences were found. Of the five patients with VZV-V four had small, deep, subcortical ischemic strokes and only one in this group had a large, cortical, hemispheric stroke but in the HIV-V group three patients had large, cortical hemispheric strokes and only one patient had small, subcortical ischemic strokes. Conclusions In this series VZV-V seemed to present more often with deep-seated ischemic infarcts, while HIVV appeared to be associated with large, hemispheric stroke. It seems plausible that this difference is related to the type of arteries infected by each virus. These findings are preliminary and should be confirmed with better studies.

Original languageEnglish (US)
Pages (from-to)145-151
Number of pages7
JournalClinical Neuroradiology
Issue number3
StatePublished - Sep 1 2011


  • Human immunodeficiency virus
  • Immunosuppression
  • Magnetic resonance imaging
  • Stroke
  • Varicella zoster virus

ASJC Scopus subject areas

  • Clinical Neurology
  • Radiology Nuclear Medicine and imaging


Dive into the research topics of 'HIV/AIDS patients with HIV vasculopathy and VZV vasculitis: A case series'. Together they form a unique fingerprint.

Cite this