Abstract
Elucidation of the mechanisms behind nuclear translocation of viral nucleic acids will lead to improvements in the design of anti-retroviral drugs and gene therapy vectors that are able to transduce non-dividing cells. A recent study has identified a triple stranded HIV cDNA intermediate of reverse transcription, or a 'central DNA flap,' as a component of HIV nuclear import.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 626-628 |
| Number of pages | 3 |
| Journal | Nature medicine |
| Volume | 6 |
| Issue number | 6 |
| DOIs | |
| State | Published - Jun 1 2000 |
| Externally published | Yes |
ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)
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Cite this
Stevenson, M. (2000). HIV nuclear import: What's the flap? Nature medicine, 6(6), 626-628. https://doi.org/10.1038/76191