HIV nuclear import: What's the flap?

Mario Stevenson

doi:10.1038/76191

HIV nuclear import: What's the flap?

Mario Stevenson

Medicine

Research output: Contribution to journal › Short survey

31 Scopus citations

Abstract

Elucidation of the mechanisms behind nuclear translocation of viral nucleic acids will lead to improvements in the design of anti-retroviral drugs and gene therapy vectors that are able to transduce non-dividing cells. A recent study has identified a triple stranded HIV cDNA intermediate of reverse transcription, or a 'central DNA flap,' as a component of HIV nuclear import.

Original language	English (US)
Pages (from-to)	626-628
Number of pages	3
Journal	Nature medicine
Volume	6
Issue number	6
DOIs	https://doi.org/10.1038/76191
State	Published - Jun 1 2000

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ASJC Scopus subject areas

Biochemistry, Genetics and Molecular Biology(all)

Cite this

Stevenson, M. (2000). HIV nuclear import: What's the flap? Nature medicine, 6(6), 626-628. https://doi.org/10.1038/76191

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10.1038/76191