Abstract
Elucidation of the mechanisms behind nuclear translocation of viral nucleic acids will lead to improvements in the design of anti-retroviral drugs and gene therapy vectors that are able to transduce non-dividing cells. A recent study has identified a triple stranded HIV cDNA intermediate of reverse transcription, or a 'central DNA flap,' as a component of HIV nuclear import.
Original language | English (US) |
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Pages (from-to) | 626-628 |
Number of pages | 3 |
Journal | Nature medicine |
Volume | 6 |
Issue number | 6 |
DOIs | |
State | Published - Jun 1 2000 |
Externally published | Yes |
ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)