HIV nuclear import: What's the flap?

Mario Stevenson

doi:10.1038/76191

HIV nuclear import: What's the flap?

Mario Stevenson

Research output: Contribution to journal › Article

31 Citations (Scopus)

Abstract

Elucidation of the mechanisms behind nuclear translocation of viral nucleic acids will lead to improvements in the design of anti-retroviral drugs and gene therapy vectors that are able to transduce non-dividing cells. A recent study has identified a triple stranded HIV cDNA intermediate of reverse transcription, or a 'central DNA flap,' as a component of HIV nuclear import.

Original language	English
Pages (from-to)	626-628
Number of pages	3
Journal	Nature Medicine
Volume	6
Issue number	6
DOIs	https://doi.org/10.1038/76191
State	Published - Jun 1 2000
Externally published	Yes

Fingerprint

Drug therapy

Gene therapy

Cell Nucleus Active Transport

Transcription

Nucleic Acids

Complementary DNA

HIV

DNA

Genetic Therapy

Reverse Transcription

Drug Therapy

ASJC Scopus subject areas

Biochemistry, Genetics and Molecular Biology(all)
Medicine(all)

Cite this

Stevenson, M. (2000). HIV nuclear import: What's the flap? Nature Medicine, 6(6), 626-628. https://doi.org/10.1038/76191

HIV nuclear import : What's the flap? / Stevenson, Mario.

In: Nature Medicine, Vol. 6, No. 6, 01.06.2000, p. 626-628.

Research output: Contribution to journal › Article

Stevenson, M 2000, 'HIV nuclear import: What's the flap?', Nature Medicine, vol. 6, no. 6, pp. 626-628. https://doi.org/10.1038/76191

Stevenson M. HIV nuclear import: What's the flap? Nature Medicine. 2000 Jun 1;6(6):626-628. https://doi.org/10.1038/76191

Stevenson, Mario. / HIV nuclear import : What's the flap?. In: Nature Medicine. 2000 ; Vol. 6, No. 6. pp. 626-628.

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Access to Document

10.1038/76191