Histoenzymological observations on three steroid dehydrogenases of submandibular gland as influenced by estrous cycle in rat

P. M. Ambadkar, A. P. Raval

Research output: Contribution to journalArticle


Some key enzymes of steroid metabolism viz.- 3α-, 3β- and 17β- hydroxysteroid dehydrogenases (HSDH) in submandibular salivary gland of female rat were studied histochemically. The results showed that these enzyme activities exhibit variation in localization as well as intensity depending on the stages of estrous cycle. 3α-HSDH activity appeared during metestrous stage and remained active through proestrous stage but waned off significantly during estrous stage, thereby indicating a stage-bound occurrence. Generally, the enzyme activities are intensely localized in the linning of granular and large collecting ducts than in acinar regions, indicating greater capacity for the steroid metabolic conversions in ducts. As regards the acini; it is suggested that the significance of these enzymes be considered as having modifying influence on metabolic patterns threat.

Original languageEnglish (US)
Pages (from-to)80-85
Number of pages6
JournalJournal of Advanced Zoology
Issue number2
StatePublished - Dec 1 1997
Externally publishedYes


ASJC Scopus subject areas

  • Animal Science and Zoology

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