Histocompatibility antigens and primary open-angle glaucoma. A reassessment

M. A. Kass, Paul Palmberg, B. Becker, J. P. Miller

Research output: Contribution to journalArticle

20 Citations (Scopus)

Abstract

Histocompatibility (HLA) antigen typing was performed on 306 patients who had been studied and classified carefully. Black individuals with primary open-angle glaucoma (POAG) had no significant differences in HLA antigen prevalences from black control subjects. In one white population with POAG, a significant decrease in HLA-A1, a significant increase in HLA-Aw31, and a significant increase in the antigen combination HLA-B7 and HLA-Bw22 were noted. However, these differences were not confirmed in a second white population with POAG. We concluded that associations between the A and B loci of the HLA antigen system and POAG were not as impressive as has been previously reported.

Original languageEnglish
Pages (from-to)2207-2208
Number of pages2
JournalArchives of Ophthalmology
Volume96
Issue number12
StatePublished - Dec 1 1978
Externally publishedYes

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Histocompatibility Antigens
HLA Antigens
HLA-A1 Antigen
HLA-B7 Antigen
Histocompatibility Testing
HLA-B Antigens
Population
Primary Open Angle Glaucoma

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Histocompatibility antigens and primary open-angle glaucoma. A reassessment. / Kass, M. A.; Palmberg, Paul; Becker, B.; Miller, J. P.

In: Archives of Ophthalmology, Vol. 96, No. 12, 01.12.1978, p. 2207-2208.

Research output: Contribution to journalArticle

Kass, MA, Palmberg, P, Becker, B & Miller, JP 1978, 'Histocompatibility antigens and primary open-angle glaucoma. A reassessment', Archives of Ophthalmology, vol. 96, no. 12, pp. 2207-2208.
Kass, M. A. ; Palmberg, Paul ; Becker, B. ; Miller, J. P. / Histocompatibility antigens and primary open-angle glaucoma. A reassessment. In: Archives of Ophthalmology. 1978 ; Vol. 96, No. 12. pp. 2207-2208.
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