Hip migration percentage in children with cerebral palsy treated with botulinum toxin type A

Frank S. Pidcock, David E. Fish, Doug Johnson-Greene, Isabel Borras, John McGready, Charles E. Silberstein

Research output: Contribution to journalArticle

33 Scopus citations

Abstract

Objective: To determine hip radiographic findings in children with cerebral palsy (CP) treated with botulinum toxin type A (BTX-A). Design: Retrospective chart review with correlation to radiographic findings. Setting: Academic center. Participants: Sixteen subjects with CP. Intervention: BTX-A treatment to adductor muscles. Main Outcome Measure: The Reimers hip migration percentage before and after BTX-A. Results: Thirty-two hips in 16 children with CP were treated. We examined the effect of initial migration percentage and initial migration percentage age on the change in migration percentage after BTX-A injection. A significant effect for initial migration percentage (<30% or ≥30%; F=19.05, P<.001) and a significant interaction between initial migration percentage and initial migration percentage age (F=7.5, P<.01) was noted. Initial migration percentage age (≤24mo or >24mo) was not significant (F=.95, P=.34). Patients who had an initial migration percentage of 30% or more and were less than 24 months old were more likely to have a decrease in migration percentage after BTX-A injection compared with patients who were older than 24 months and who had an initial migration percentage of 30% or more. Conclusions: Improvement in hip migration percentage after BTX-A injection is a function of age and the initial migration percentage. BTX-A injections to adductor muscles may be beneficial for some children with CP.

Original languageEnglish (US)
Pages (from-to)431-435
Number of pages5
JournalArchives of physical medicine and rehabilitation
Volume86
Issue number3
DOIs
StatePublished - Mar 2005
Externally publishedYes

Keywords

  • Botulinum toxin type A
  • Cerebral palsy
  • Hip
  • Rehabilitation

ASJC Scopus subject areas

  • Rehabilitation

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