Highly chromic, proton-responsive phenyl pyrimidones

Jyothi Dhuguru, Chirag Gheewala, N. S.Saleesh Kumar, James N. Wilson

Research output: Contribution to journalArticlepeer-review

12 Scopus citations


Aryl pyrimidones are pharmacologically relevant compounds whose optical properties have only been partially explored. We report the synthesis and optical characterization of a series of aryl- and diaryl-2(1H)-pyrimidones. The electronic transitions of these chromophores are modulated by the extent of conjugation between the pendant phenyl ring and the pyrimidone core as well as the presence of electron-donating auxochromes. Monoprotonation of the pyrimidone ring results in large hyperchromic and bathochromic shifts as well as switching of fluorescence making these phenyl pyrimidones of interest as sensory materials.

Original languageEnglish (US)
Pages (from-to)4188-4191
Number of pages4
JournalOrganic letters
Issue number16
StatePublished - Aug 19 2011

ASJC Scopus subject areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry


Dive into the research topics of 'Highly chromic, proton-responsive phenyl pyrimidones'. Together they form a unique fingerprint.

Cite this