High Incidence of Tuberculosis Infection in HIV-exposed Children Exiting an Isoniazid Preventive Therapy Trial

IMPAACT P1041 Team

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Young HIV-exposed children are at high risk for TB infection. We performed QuantiFERON-TB Gold among HIV-exposed children in South Africa at enrolment and 1-year follow-up. The incidence of TB infection was high for HIV+ (11 cases per 100 child-years) and HIV-exposed uninfected children (15 cases per 100 child-years). QuantiFERON-TB Gold may identify HIV-exposed children at risk for TB disease progression.

Original languageEnglish (US)
Pages (from-to)e254-e256
JournalThe Pediatric infectious disease journal
Volume37
Issue number10
DOIs
StatePublished - Oct 1 2018

Fingerprint

Isoniazid
HIV Infections
Tuberculosis
HIV
Incidence
Gold
Therapeutics
South Africa
Infection
Disease Progression

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Microbiology (medical)
  • Infectious Diseases

Cite this

High Incidence of Tuberculosis Infection in HIV-exposed Children Exiting an Isoniazid Preventive Therapy Trial. / IMPAACT P1041 Team.

In: The Pediatric infectious disease journal, Vol. 37, No. 10, 01.10.2018, p. e254-e256.

Research output: Contribution to journalArticle

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