High-dose propranolol therapy in the management of supraventricular tachycardia

Arthur S. Pickoff, Leonor Zies, Pedro L. Ferrer, Dolores Tamer, Grace Wolff, Otto Garcia, Henry Gelband

Research output: Contribution to journalArticle

35 Citations (Scopus)

Abstract

Five patients age 3 weeks to 11 years, presented with supraventricular tachycardia that remained uncontrolled following adequate digitalization. Four of these patients underwent invasive electrophysiologic studies to determine the mechanism of the arrhythmias. Of these four patients, three had concealed Wolff-Parkinson-White syndrome, and one patient had evidence of dual A-V nodal pathways. Propranolol was added to the medical treatment and was administered orally in doses ranging from 7 to 14 mg/kg/day (average 9 mg/kg/day). All five children remain free of their tachycardia except for one patient who occasionally has supraventricular tachycardia with febrile illnesses. No adverse reactions to these high doses of propranolol were encountered.

Original languageEnglish
Pages (from-to)144-146
Number of pages3
JournalThe Journal of pediatrics
Volume94
Issue number1
DOIs
StatePublished - Jan 1 1979
Externally publishedYes

Fingerprint

Supraventricular Tachycardia
Propranolol
Therapeutics
Wolff-Parkinson-White Syndrome
Tachycardia
Cardiac Arrhythmias
Fever

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

Cite this

Pickoff, A. S., Zies, L., Ferrer, P. L., Tamer, D., Wolff, G., Garcia, O., & Gelband, H. (1979). High-dose propranolol therapy in the management of supraventricular tachycardia. The Journal of pediatrics, 94(1), 144-146. https://doi.org/10.1016/S0022-3476(79)80381-9

High-dose propranolol therapy in the management of supraventricular tachycardia. / Pickoff, Arthur S.; Zies, Leonor; Ferrer, Pedro L.; Tamer, Dolores; Wolff, Grace; Garcia, Otto; Gelband, Henry.

In: The Journal of pediatrics, Vol. 94, No. 1, 01.01.1979, p. 144-146.

Research output: Contribution to journalArticle

Pickoff, AS, Zies, L, Ferrer, PL, Tamer, D, Wolff, G, Garcia, O & Gelband, H 1979, 'High-dose propranolol therapy in the management of supraventricular tachycardia', The Journal of pediatrics, vol. 94, no. 1, pp. 144-146. https://doi.org/10.1016/S0022-3476(79)80381-9
Pickoff, Arthur S. ; Zies, Leonor ; Ferrer, Pedro L. ; Tamer, Dolores ; Wolff, Grace ; Garcia, Otto ; Gelband, Henry. / High-dose propranolol therapy in the management of supraventricular tachycardia. In: The Journal of pediatrics. 1979 ; Vol. 94, No. 1. pp. 144-146.
@article{efb8a480e6f8435e8e2ae1b6ff661f9c,
title = "High-dose propranolol therapy in the management of supraventricular tachycardia",
abstract = "Five patients age 3 weeks to 11 years, presented with supraventricular tachycardia that remained uncontrolled following adequate digitalization. Four of these patients underwent invasive electrophysiologic studies to determine the mechanism of the arrhythmias. Of these four patients, three had concealed Wolff-Parkinson-White syndrome, and one patient had evidence of dual A-V nodal pathways. Propranolol was added to the medical treatment and was administered orally in doses ranging from 7 to 14 mg/kg/day (average 9 mg/kg/day). All five children remain free of their tachycardia except for one patient who occasionally has supraventricular tachycardia with febrile illnesses. No adverse reactions to these high doses of propranolol were encountered.",
author = "Pickoff, {Arthur S.} and Leonor Zies and Ferrer, {Pedro L.} and Dolores Tamer and Grace Wolff and Otto Garcia and Henry Gelband",
year = "1979",
month = "1",
day = "1",
doi = "10.1016/S0022-3476(79)80381-9",
language = "English",
volume = "94",
pages = "144--146",
journal = "Journal of Pediatrics",
issn = "0022-3476",
publisher = "Mosby Inc.",
number = "1",

}

TY - JOUR

T1 - High-dose propranolol therapy in the management of supraventricular tachycardia

AU - Pickoff, Arthur S.

AU - Zies, Leonor

AU - Ferrer, Pedro L.

AU - Tamer, Dolores

AU - Wolff, Grace

AU - Garcia, Otto

AU - Gelband, Henry

PY - 1979/1/1

Y1 - 1979/1/1

N2 - Five patients age 3 weeks to 11 years, presented with supraventricular tachycardia that remained uncontrolled following adequate digitalization. Four of these patients underwent invasive electrophysiologic studies to determine the mechanism of the arrhythmias. Of these four patients, three had concealed Wolff-Parkinson-White syndrome, and one patient had evidence of dual A-V nodal pathways. Propranolol was added to the medical treatment and was administered orally in doses ranging from 7 to 14 mg/kg/day (average 9 mg/kg/day). All five children remain free of their tachycardia except for one patient who occasionally has supraventricular tachycardia with febrile illnesses. No adverse reactions to these high doses of propranolol were encountered.

AB - Five patients age 3 weeks to 11 years, presented with supraventricular tachycardia that remained uncontrolled following adequate digitalization. Four of these patients underwent invasive electrophysiologic studies to determine the mechanism of the arrhythmias. Of these four patients, three had concealed Wolff-Parkinson-White syndrome, and one patient had evidence of dual A-V nodal pathways. Propranolol was added to the medical treatment and was administered orally in doses ranging from 7 to 14 mg/kg/day (average 9 mg/kg/day). All five children remain free of their tachycardia except for one patient who occasionally has supraventricular tachycardia with febrile illnesses. No adverse reactions to these high doses of propranolol were encountered.

UR - http://www.scopus.com/inward/record.url?scp=0018328624&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0018328624&partnerID=8YFLogxK

U2 - 10.1016/S0022-3476(79)80381-9

DO - 10.1016/S0022-3476(79)80381-9

M3 - Article

VL - 94

SP - 144

EP - 146

JO - Journal of Pediatrics

JF - Journal of Pediatrics

SN - 0022-3476

IS - 1

ER -